Autonomic nervous system functions in childhood essential hypertension

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dc.authoridYakıncı, Mehmet Cengiz/0000-0001-5930-4269
dc.authorwosidYakıncı, Mehmet Cengiz/ABI-7519-2020
dc.contributor.authorYakinci, C
dc.contributor.authorMungen, B
dc.contributor.authorTayfun, M
dc.contributor.authorGunduz, M
dc.contributor.authorKarabiber, H
dc.date.accessioned2024-08-04T20:11:50Z
dc.date.available2024-08-04T20:11:50Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe etiopathology of essential hypertension (EH) is still controversial, different pathologic mechanisms have been estimated as a cause of EH. One of these mechanisms is autonomic nervous system dysfunction (ANSD). Although there are different studies showing ANSD in adult EH, limited studies on ANSD in childhood EH are present. The present study was planned to investigate the role of ANSD in childhood EH. The study group (SG) consisted of 24 children with EH and the control group (CG) was 24 healthy children. Non-invasive autonomic nervous system function tests: the orthostatic test, Valsalva ratio, 30/15 ratio and heart rate responses to deep breathing were performed on members of both groups. The mean differences in systolic blood pressure between supine resting and standing positions in the study and control groups were significant (z = -2.577, P = 0.0051). The mean differences in diastolic blood pressure between supine resting and standing positions in SG and CG were found to be statistically meaningful (z = -2.722, P = 0.0033). The mean differences in heart rate variation during hyperventilation in SG and CG were significant (z = -2.54, P = 0.0055). The mean differences in the Valsalva ratio between SG and CG were not statistically meaningful (z = 1.52, P = 0.0643). The mean differences in the 30/15 ratio in SG and CG were not found to be significant (z = -1.455, P = 0.0735). In the light of these results, both sympathetic and parasympathetic autonomic nervous system dysfunction in childhood essential hypertension were found.en_US
dc.identifier.endpage613en_US
dc.identifier.issn0374-5600
dc.identifier.issue6en_US
dc.identifier.pmid9002295en_US
dc.identifier.scopus2-s2.0-0029856035en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage611en_US
dc.identifier.urihttps://hdl.handle.net/11616/93028
dc.identifier.volume38en_US
dc.identifier.wosWOS:A1996WB39300010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Scienceen_US
dc.relation.ispartofActa Paediatrica Japonicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautonomic nervous systemen_US
dc.subjectchildhooden_US
dc.subjectessential hypertensionen_US
dc.titleAutonomic nervous system functions in childhood essential hypertensionen_US
dc.typeArticleen_US

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