Evaluation of the left ventricular function with tissue tracking and tissue Doppler echocardiography in pediatric malignancy survivors after anthracycline therapy

dc.authoridKARAKURT, CEMŞIT/0000-0002-9246-8107
dc.authorwosidKARAKURT, CEMŞIT/ABE-2330-2020
dc.contributor.authorKarakurt, Cemsit
dc.contributor.authorKocak, Gulendam
dc.contributor.authorOzgen, Unsal
dc.date.accessioned2024-08-04T20:30:58Z
dc.date.available2024-08-04T20:30:58Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAlthough the anthracyclines have gained widespread use in the treatment of childhood hematological malignancies and solid tumors, cardiotoxicity is the major limiting factor in the use of anthracyclines. The aim of this study was to assess the mitral annular displacement by tissue tracking in pediatric malignancy survivors who had been treated with anthracycline groups chemotheraphy and compare with the tissue Doppler and conventional two dimensional measurements and Doppler indices. In this study, 32 pediatric malignancy survivors and 22 healthy children were assessed with 2D, colour-coded echocardiography. Left ventricular ejection fraction, fractional shortening, stroke volume, cardiac output, cardiac index and diastolic functions were measured. All subjects were assessed with tissue Doppler echocardiography, mitral annular displacements, and also with tissue tracking method. We detected that peak velocity of the early rapid filling on tissue Doppler (E') was lower (p < 0.05) and the ratio of early peak velocity of rapid filling on pulse Doppler to tissue Doppler (E/E') values were statistically higher in patient group than control group (p < 0.05). Myocardial performance index values were also higher in patient group than the control group (p < 0.01). It appears that MPI is a useful echocardiograghic method than tissue tracking of mitral annular displacement in patients with pediatric cancer survivors who had subclinical diastolic dysfunction.en_US
dc.identifier.doi10.1111/j.1540-8175.2008.00695.x
dc.identifier.endpage887en_US
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue8en_US
dc.identifier.pmid18986416en_US
dc.identifier.scopus2-s2.0-51349151180en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage880en_US
dc.identifier.urihttps://doi.org/10.1111/j.1540-8175.2008.00695.x
dc.identifier.urihttps://hdl.handle.net/11616/94644
dc.identifier.volume25en_US
dc.identifier.wosWOS:000259147300011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEchocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectanthracycline cardiotoxicityen_US
dc.subjecttissue Doppleren_US
dc.subjecttissue trackingen_US
dc.subjectmyocardial performance indexen_US
dc.titleEvaluation of the left ventricular function with tissue tracking and tissue Doppler echocardiography in pediatric malignancy survivors after anthracycline therapyen_US
dc.typeArticleen_US

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