Elevated plasma homocysteine level in slow coronary flow

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dc.authoridgüllü, hakan/0000-0003-2579-9755;
dc.authorwosidgüllü, hakan/IXD-5147-2023
dc.authorwosidKutlusoy, Ergun/ABB-9017-2020
dc.contributor.authorBarutcu, I
dc.contributor.authorSezgin, AT
dc.contributor.authorSezgin, N
dc.contributor.authorGullu, H
dc.contributor.authorEsen, AM
dc.contributor.authorTopal, E
dc.contributor.authorOzdemir, R
dc.date.accessioned2024-08-04T20:14:43Z
dc.date.available2024-08-04T20:14:43Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Slow flow velocity of dye in coronary arteries is not an infrequent finding during routine coronary angiography and its precise mechanism is unknown. In this study, we measured the plasma homocysteine level in patients with slow coronary flow (SCF) in comparison with subjects having normal coronary flow (NCF). Method: The study consisted 39 patients (mean age, 47 +/- 8 years) with angiographically diagnosed SCF. SCF was defined according to TIMI frame count (TFC) method. Thirty subjects (mean age 46 8 years) with NCF served as control group. Plasma homocysteine levels were measured after 12 h fasting period in each subject. Results: Baseline demographic properties were similar in both groups. In patients with SCF, TFC was significantly higher than those with NCF. Similarly, in patients with SCF plasma homocysteine level was significantly higher than that of control group (14.1 +/- 2.2 vs. 5.5 +/- 1.3 mu mol/l, respectively p < 0.001). Conclusion: Elevated plasma homocysteine level supports the hypothesis that endothelial function is impaired in slow coronary flow. (c) 2004 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijcard.2004.01.030
dc.identifier.endpage145en_US
dc.identifier.issn0167-5273
dc.identifier.issue1en_US
dc.identifier.pmid15860399en_US
dc.identifier.scopus2-s2.0-18144412697en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijcard.2004.01.030
dc.identifier.urihttps://hdl.handle.net/11616/93902
dc.identifier.volume101en_US
dc.identifier.wosWOS:000229248200024en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal of Cardiologyen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectslow coronary flowen_US
dc.subjecthyperhomocysteinemiaen_US
dc.subjectendothelial dysfunctionen_US
dc.titleElevated plasma homocysteine level in slow coronary flowen_US
dc.typeLetteren_US

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