Ürdün’ün kuzey bölgesindeki kan donörlerinde toxoplasma gondii antikorunun ıgg, ıgm prevalansı
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Dosyalar
Tarih
2004
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
Attribution 3.0 United States
Özet
Ürdün’ün Kuzey bölümünde yaşayan 1500 uygun kan donörü Toxoplasma gondii antikoru varlığı yönündentarandı. Bu çalışmanın amacı, Ürdün populasyonundaki kan donörlerinde Toxoplasma gondii antikorunun (IgG,IgM) seroprevalansını değerlendirmektir. Bu amaçla 1999 yılında Prince Rashid Bin Al-Hassan MilitaryHospital’da retrospektif bir çalışma yapıldı ve veriler toplandı. Bütün donörlerden taze kan örnekleri alınarak,serumlar ayrıldı ve test yapılana kadar -20 ºC’de saklandı. Toxoplasma gondii antikorları IgG, IgM ELISA testi(DiaSorin Entities, ETI -Toxok-G plus) kullanılarak, toplam 1500 kan donörü (1200 erkek, 300 kadın)Toxoplasma gondii IgG and IgM antikorları yönünden incelendi. Çalışma populasyonu içerisinde Toxoplasmagondii IgM antikorları saptanmadı.Toxoplasma gondii IgG olgularının prevalansı %35.5 olarak belirlenirken erkek ve kadınların prevalansları ise sırası ile %35.8 ve %34.3 bulundu. Toxoplasma gondii pozitif donörlerin pik yaş aralığı 20-29 olarak belirlendi.Donörlerimizde seropozitiflik oranının belirgin olarak yüksek olduğu kararına varıldı. Bu nedenle, genişletilmişimmünizasyon programları oluşturularak, bütün yaş gruplarına uygulanması, Toxoplasma gondii markırlarının ölçümünde daha duyarlı tarama yöntemleri kullanılarak, daha geniş poplusyonlarda Toxoplasma gondi iprevalansının saptanması gerektiği kanısına varılmıştır .
A total of 1500 blood donors were examined for Toxoplasma gondii antibodies (IgG), and (IgM), by serological techniques. Eighty normal cross matched controls were subjected to the same examination.The aim of this study is to examine the sero prevalence rate of Toxoplasma gondii in northern region of Jordan population among blood donors. A retrospective study was carried out at Prince Rashid Bin Al-Hassan Military Hospital in the north region of Jordan over one year period in 1999.Fresh blood samples were randomly drawn from all donors. Serum was separated and stored at -20 Cº until it was tested. Toxoplasma gondii antibodies were detected using the Enzyme Linked Immunosorbent Assay (ELISA ).A total of 1500 (1200 males, 300 females) blood donors were screened for toxoplasma gondii antibodies IgG and IgM. The prevalence of toxoplasma among the study population was 35.5% and the prevalence in males and females were 35.8% and 34.3% , respectively.The peak age range of toxoplasma gondii antibodies IgG donors among males 20 to 29 years; followed 30 to 39,40 to 49, and< 20 years respectively. Among the female donors, the highest detection of Toxoplasma gondi iantibodies IgG was between the ages of 20 to 29, followed by 30 to 39 years, < 20 years and by age from 40-49 years, respectively.The lowest seropositivity was in the age group ≥ 50 years among males and females. So we concluded that seropositivity in our donors was significant, and previous studies carried out in Jordan and other countries indicated the high prevalence of Toxoplasma gondii infection.The results obtained in this study, expanded immunization programme must be introduced considering all age groups. Future studies are necessary to determine the prevalence of Toxoplasma gondii antibodies in more common populations by using sensitive screening methods
A total of 1500 blood donors were examined for Toxoplasma gondii antibodies (IgG), and (IgM), by serological techniques. Eighty normal cross matched controls were subjected to the same examination.The aim of this study is to examine the sero prevalence rate of Toxoplasma gondii in northern region of Jordan population among blood donors. A retrospective study was carried out at Prince Rashid Bin Al-Hassan Military Hospital in the north region of Jordan over one year period in 1999.Fresh blood samples were randomly drawn from all donors. Serum was separated and stored at -20 Cº until it was tested. Toxoplasma gondii antibodies were detected using the Enzyme Linked Immunosorbent Assay (ELISA ).A total of 1500 (1200 males, 300 females) blood donors were screened for toxoplasma gondii antibodies IgG and IgM. The prevalence of toxoplasma among the study population was 35.5% and the prevalence in males and females were 35.8% and 34.3% , respectively.The peak age range of toxoplasma gondii antibodies IgG donors among males 20 to 29 years; followed 30 to 39,40 to 49, and< 20 years respectively. Among the female donors, the highest detection of Toxoplasma gondi iantibodies IgG was between the ages of 20 to 29, followed by 30 to 39 years, < 20 years and by age from 40-49 years, respectively.The lowest seropositivity was in the age group ≥ 50 years among males and females. So we concluded that seropositivity in our donors was significant, and previous studies carried out in Jordan and other countries indicated the high prevalence of Toxoplasma gondii infection.The results obtained in this study, expanded immunization programme must be introduced considering all age groups. Future studies are necessary to determine the prevalence of Toxoplasma gondii antibodies in more common populations by using sensitive screening methods
Açıklama
İnönü Üniversitesi Tıp Fakültesi Dergisi
11(3) 143-146 (2004)
Anahtar Kelimeler
Toxoplasma gondii, Kan donörleri, Blood donors
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Abdülgani, Fethi ;İnönü Üniversitesi Tıp Fakültesi Dergisi 11(3) 143-146 (2004)
