EVALUATION OF THE YIELDS AND ANTIOXIDANT ACTIVITIES OF ESSENTIAL OILS, FIXED OILS AND EXTRACTS OBTAINED USING CONVENTIONAL METHODS FROM NIGELLA SATIVA L. AND NIGELLA DAMASCENA L. SEEDS

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dc.contributor.authorÇaprak, Burak Emre
dc.contributor.authorShahbazi, Fatemeh
dc.contributor.authorTorun, Zehra
dc.date.accessioned2026-04-04T13:19:05Z
dc.date.available2026-04-04T13:19:05Z
dc.date.issued2026
dc.departmentİnönü Üniversitesi
dc.description.abstractObjective: Yields and antioxidant properties of essential oils, fixed oils, and extracts from Nigella sativa L. and Nigella damascena L. seeds were evaluated using conventional extraction methods with solvents of different polarity. Material and Method: The seeds from both species were divided into three segments for the production of fixed oil, essential oil, and essential oil from extracts. Fixed oils and extracts were obtained using Soxhlet extraction with n-hexane, petroleum ether, acetone, chloroform, and methanol, followed by hydrodistillation using a Clevenger apparatus to obtain essential oils from the extracts. Essential oils were also obtained from powdered seeds by hydrodistillation. Oils and extract yields were calculated, and antioxidant activities were evaluated using DPPH. and ABTS+ assays. Result and Discussion: For both species, the continuous extraction method with n-hexane produced the highest yield and the essential oils were obtained only from these extracts. Notably, extracting the essential oil directly from the seed resulted in low yields. N. sativa exhibited higher essential oil yields than N. damascena; however, the obtained yields were inadequate for activity studies. Antioxidant assays revealed that the ABTS⁺ method was more discriminative, with acetone extracts showing higher activity. Overall, N. sativa demonstrated greater antioxidant activity compared to N. damascena. © 2026, University of Ankara. All rights reserved.
dc.description.sponsorshipTürkiye Bilimsel ve Teknolojik Araştırma Kurumu, TUBITAK, (1919B012210600); Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TUBITAK
dc.identifier.doi10.33483/jfpau.1618266
dc.identifier.endpage105
dc.identifier.issn1015-3918
dc.identifier.issue1
dc.identifier.scopus2-s2.0-105028891789
dc.identifier.scopusqualityQ4
dc.identifier.startpage97
dc.identifier.urihttps://doi.org/10.33483/jfpau.1618266
dc.identifier.urihttps://hdl.handle.net/11616/108130
dc.identifier.volume50
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherUniversity of Ankara
dc.relation.ispartofAnkara Universitesi Eczacilik Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250329
dc.subjectAntioxidant activity
dc.subjectessential oil
dc.subjectfixed oil
dc.subjectNigella damascene
dc.subjectNigella sativa
dc.titleEVALUATION OF THE YIELDS AND ANTIOXIDANT ACTIVITIES OF ESSENTIAL OILS, FIXED OILS AND EXTRACTS OBTAINED USING CONVENTIONAL METHODS FROM NIGELLA SATIVA L. AND NIGELLA DAMASCENA L. SEEDS
dc.title.alternativeNIGELLA SATIVA L. VE NIGELLA DAMASCENA L. TOHUMLARINDAN KONVANSİYONEL YÖNTEMLER İLE ELDE EDİLEN UÇUCU YAĞ, SABİT YAĞ VE EKSTRELERİN VERİM VE ANTİOKSİDAN AKTİVİTELERİNİN DEĞERLENDİRİLMESİ]
dc.typeArticle

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