Konjenital diafragma hernisinde yaşam prediktörleri: 10 yıllık deneyimin multivariate analizi
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Dosyalar
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmanın amacı KDH’li hastalarda kurtarma tedavisine almak için hangi bağımsız yaşam prediktöderinin olduğunun ve kullanılabileceğinin tespiti için bir metod geliştirmekti. Merkezimizin 10 yıllık bir süredeki 62 hastasının verileri analiz edildi. 15 preoperatif ve 7 intraoperatif değişken incelendi. Stepwise lojistik regresyon analizi
olduğu sonucunu verdi: düşük VI, yüksek DA, yüksek 5 dakika APGAR sonucu ve düşük PaC02. Yaşam probabilitesi %20’den küçük kriterini kullanarak yapılan değerlendirme konvansiyel tedaviden fayda görmeyecek KDH’li vakaların değerlendirilmesinde %94 sensitivite ve %82 spesifite sonucunu verdi. Sonuç olarak VI in preoperatif değeri, DA, 5 dakika APGAR, ve PaC02 kurtarma tedavisinden fayda görebilecek, yüksek mortalite öngörülen yenidoğanların seçiminde kullanılabilir düşüncesindeyiz.
The purpose of this study was to establish a method by which independent predictors of survival could be determined and used to select CDHpatients who may benefit from rescue therapy. Data from our 10-year, single institutional experience of 62 infants with CDH were analyzed. Fifteen preoperative and seven intraoperative variables were analyzed. Stepwise logistic regression analysis yielded a prediction equation with four independent, statistically significant (P<0.05) predictors of survival: lower VI, higher BW, higher 5-minute APGAR, and lower PaCO2. Using a survival probability of <20%, this equation yielded a sensitivity of 94% and specificity of 82% in selecting those patients with CDH who failed conventional management. We conclude that the preoperative values for VI, BW, 5-minute APGAR, and PaCO2 of neonates with CDH in our institution can be used to select those patients with predicted high mortality who may benefit from salvage therapy.
The purpose of this study was to establish a method by which independent predictors of survival could be determined and used to select CDHpatients who may benefit from rescue therapy. Data from our 10-year, single institutional experience of 62 infants with CDH were analyzed. Fifteen preoperative and seven intraoperative variables were analyzed. Stepwise logistic regression analysis yielded a prediction equation with four independent, statistically significant (P<0.05) predictors of survival: lower VI, higher BW, higher 5-minute APGAR, and lower PaCO2. Using a survival probability of <20%, this equation yielded a sensitivity of 94% and specificity of 82% in selecting those patients with CDH who failed conventional management. We conclude that the preoperative values for VI, BW, 5-minute APGAR, and PaCO2 of neonates with CDH in our institution can be used to select those patients with predicted high mortality who may benefit from salvage therapy.
Açıklama
[Journal of Turgut Özal Medical Center 1997;4(2):225-229]
Anahtar Kelimeler
Konjenital, Diafragmatik, Herni, Yenidoğan, Pediatric, Hernia, Diaphragmatic, Congenital, Outcome, Newborn, Pediatrics
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
2
Künye
Gürsoy, M. Harun.,Shew, Stephen B.,Miller, Ronna G.,Smith, E. O’Brian.,Gomez, Michael R. ,Jaksic, Tom.,(1997). Konjenital diafragma hernisinde yaşam prediktörleri: 10 yıllık deneyimin multivariate analizi.Turgut Özal Tıp Merkezi Dergisi, 4 (2).225-229 ss.
