Association between elevated aminotransferase levels and the metabolic syndrome in Northern Turkey

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dc.authoridOZYURT, Huseyin/0000-0003-2327-4082
dc.authoridÖzdemir, Metin/0000-0001-9678-0862
dc.authoridSahin, Idris/0000-0002-8683-3737
dc.authorwosidOZYURT, Huseyin/N-4351-2015
dc.authorwosidÖzdemir, Metin/HJO-8584-2023
dc.authorwosidSahin, Idris/AAS-4390-2020
dc.contributor.authorYildirim, Beytullah
dc.contributor.authorOzugurlu, Fikret
dc.contributor.authorSahin, Semsettin
dc.contributor.authorOzyurt, Huseyin
dc.contributor.authorAtis, Omer
dc.contributor.authorAkbas, Ali
dc.contributor.authorAkturk, Yeliz
dc.date.accessioned2024-08-04T20:32:31Z
dc.date.available2024-08-04T20:32:31Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction. Elevated aminotransferase levels(ATLs) are alert the physicians for liver-affecting disease and may reflect liver injury. We aimed to determine the prevalence of elevated ATLs and the association of elevated ATLs with the metabolic syndrome(MetS) in a northern province of Turkey. Materials and methods. Elevated ATLs were evaluated among 1,095 individuals of the Tokat Prevalence Study which have been described in detail elsewhere. 1,095 participants had been selected by a simple random sampling method among 530,000 inhabitants in 70 (12 urban and 58 rural) areas in the province of Tokat which is located in the Black Sea Region of Turkey. Results. The prevalence of elevated serum ALT, AST, and ALT and/or AST were found as 11%, 7.2%, and 13.3%, respectively. Increased BMI, fatty liver, and MetS were higher in our general population with elevated ATLs. After exclusion of individuals with hepatitis B or hepatitis C infection, 132 individuals with elevated ATLs (91 male and 41 female) were evaluated. MetS was found in 59 participants and its prevalence was markedly higher in females with elevated ATLs (p < 0.0001). When the males with elevated ATLs were evaluated, the ALT levels of the persons who have no risk of MetS (p = 0.007) and the persons who have one risk of MetS (p = 0.001) were lower than the persons with MetS. Conclusions. Elevated ATLs are common and it's an important cause is MetS in Northern Turkey.en_US
dc.description.sponsorshipGaziosmanpasa University [2005/26]en_US
dc.description.sponsorshipThis project was funded by The Society of Science Research Projects in Gaziosmanpasa University, Project number: 2005/26.en_US
dc.identifier.doi10.1016/S1665-2681(19)31655-2
dc.identifier.endpage165en_US
dc.identifier.issn1665-2681
dc.identifier.issue2en_US
dc.identifier.pmid20526009en_US
dc.identifier.scopus2-s2.0-77956633767en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1016/S1665-2681(19)31655-2
dc.identifier.urihttps://hdl.handle.net/11616/95127
dc.identifier.volume9en_US
dc.identifier.wosWOS:000279379200006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMexican Assoc Hepatologyen_US
dc.relation.ispartofAnnals of Hepatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElevated aminotransferase levelsen_US
dc.subjectMetabolic syndromeen_US
dc.subjectRisk factorsen_US
dc.subjectTurkeyen_US
dc.titleAssociation between elevated aminotransferase levels and the metabolic syndrome in Northern Turkeyen_US
dc.typeArticleen_US

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