Comparison of effects of low-flow and normal-flow anesthesia on cerebral oxygenation and bispectral index in morbidly obese patients undergoing laparoscopic sleeve gastrectomy: a prospective, randomized clinical trial

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dc.authoridAkbas, Sedat/0000-0003-3055-9334
dc.authoridOzkan, Ahmet Selim/0000-0002-4543-8853
dc.authorwosidAkbas, Sedat/ABI-6053-2020
dc.authorwosidOzkan, Ahmet Selim/ABH-2918-2020
dc.contributor.authorAkbas, Sedat
dc.contributor.authorOzkan, Ahmet Selim
dc.date.accessioned2024-08-04T20:45:42Z
dc.date.available2024-08-04T20:45:42Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: The effects of low-flow anesthesia on cerebral oxygenation in high-risk, morbidly obese patients are not well known. Aim: In this prospective randomized study, we compared the effects of low-flow (0.75 l/min) and normal-flow (1.5 l/min) anesthesia on regional cerebral oxygen saturation (rSO(2)) and the bispectral index (BIS) in morbidly obese patients undergoing laparoscopic bariatric surgery. Material and methods: Fifty-two morbidly obese patients undergoing laparoscopic bariatric surgery (sleeve gastrectomy) were enrolled in this study. Patients were randomly allocated to two study groups: low flow and normal-flow anesthesia groups. Heart rate, mean arterial pressure, peripheral oxygen saturation, end-tidal carbon dioxide, BIS, left and right rSO(2) and duration of anesthesia and surgery were recorded. Results: The groups were similar with respect to age, gender, height, weight, body mass index, American Society of Anesthesiology physical status, heart rate, duration of anesthesia, and procedure. Mean arterial pressure and end-tidal carbon dioxide, both before and after insufflation of carbon dioxide and after the reverse Trendelenburg position, were significantly higher in the low-flow group. BIS values and left and right rSO(2) during the preoperative and intraoperative periods were similar. Although the difference in right rSO(2) between the two groups after awakening from anesthesia was statistically significant, the results of both groups remained within the normal range and were not clinically meaningful. Conclusions: Low-flow anesthesia is safe regarding hemodynamic and respiratory characteristics, depth of anesthesia, and regional cerebral oxygen saturation in morbidly obese patients undergoing laparoscopic bariatric surgery.en_US
dc.identifier.doi10.5114/wiitm.2018.77265
dc.identifier.endpage26en_US
dc.identifier.issn1895-4588
dc.identifier.issn2299-0054
dc.identifier.issue1en_US
dc.identifier.pmid30766625en_US
dc.identifier.scopus2-s2.0-85061111383en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage19en_US
dc.identifier.urihttps://doi.org/10.5114/wiitm.2018.77265
dc.identifier.urihttps://hdl.handle.net/11616/98641
dc.identifier.volume14en_US
dc.identifier.wosWOS:000457117600004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofVideosurgery and Other Miniinvasive Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmorbid obesityen_US
dc.subjectbispectral indexen_US
dc.subjectbariatric/metabolic surgeryen_US
dc.subjectanesthesia managementen_US
dc.subjectlow flow anesthesiaen_US
dc.subjectregional cerebral oximetryen_US
dc.titleComparison of effects of low-flow and normal-flow anesthesia on cerebral oxygenation and bispectral index in morbidly obese patients undergoing laparoscopic sleeve gastrectomy: a prospective, randomized clinical trialen_US
dc.typeArticleen_US

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