A comparison of the measurements with biochemical markers of bone turnover and bone mineral density in the assessment of the efficiency of osteoporosis treatment

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dc.authoridAtaoğlu, Baybars/0000-0003-1359-7013;
dc.authorwosidAtaoğlu, Muhammet Baybars/D-5188-2016
dc.authorwosidAtaoğlu, Baybars/AAX-9031-2021
dc.authorwosidSarikaya, Baran/AAA-8515-2021
dc.contributor.authorAtaoglu, M. Baybars
dc.contributor.authorAtik, O. Sahap
dc.contributor.authorGul, Orkun
dc.contributor.authorSarikaya, Baran
dc.contributor.authorGormeli, Gokay
dc.contributor.authorOzturk, Burak Yagmur
dc.contributor.authorOzgurol, Baris
dc.date.accessioned2024-08-04T20:37:36Z
dc.date.available2024-08-04T20:37:36Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: This study aims to compare the measurements using biochemical markers of bone turnover and bone mineral density (BMD) in the assessment of the efficiency of osteoporosis treatment. Patients and methods: Between March 2006 and December 2008, 166 patients with osteoporosis in our clinic were included. Patients who were out of contact due to death or other reasons during follow-up were excluded. We compared the measurements of urinary biochemical markers of bone turnover using cross-linked N-telopeptide (Ntx) values and BMD in 60 patients (49 females, 11 males; mean age: 65.7 years; range: 42 to 87 years) with osteoporosis who were treatment-naive and completed study. Results: Twenty-nine (48.3%) of the patients received surgical treatment, while 31 (51.7%) received conservative therapy. Urine NTx values of the patients decreased 38.82% at three months; 51.99% at six months and 66.41% at 12 months. Lumbar vertebra BMD increased by 20.7% and femur neck BMD increased by 11.9% at the end of the first year. Conclusion: Urine NTx values respond to osteoporosis treatment faster than BMD measurements; thereby it may be suitable to use this parameter for the monitorization of the treatment efficiency.en_US
dc.identifier.doi10.5606/ehc.2013.19
dc.identifier.endpage86en_US
dc.identifier.issn1305-8282
dc.identifier.issn1309-0313
dc.identifier.issue2en_US
dc.identifier.pmid23692194en_US
dc.identifier.scopus2-s2.0-84878359664en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.5606/ehc.2013.19
dc.identifier.urihttps://hdl.handle.net/11616/96073
dc.identifier.volume24en_US
dc.identifier.wosWOS:000322682200005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTurkish Joint Diseases Foundationen_US
dc.relation.ispartofEklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone mineral densityen_US
dc.subjectcross-linked N-telopeptideen_US
dc.subjectosteoporosisen_US
dc.subjecturineen_US
dc.titleA comparison of the measurements with biochemical markers of bone turnover and bone mineral density in the assessment of the efficiency of osteoporosis treatmenten_US
dc.typeArticleen_US

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