Correlation of clinical target volume and the margins to define planning target volume with beam arrangements for three-dimensional conformal radiation therapy delivery for prostate cancer

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dc.authorscopusid6603777920
dc.authorscopusid7004027424
dc.contributor.authorErkal H.Ş.
dc.contributor.authorSerin M.
dc.date.accessioned2024-08-04T20:02:19Z
dc.date.available2024-08-04T20:02:19Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. A conceptual study was undertaken to correlate the clinical target volume and the margins to define the planning target volume with the beam arrangements for a three-dimensional conformal radiation therapy delivery on two patients with prostate cancer having considerably different prostate shapes and volumes. Material and methods. The clinical target volume was defined as prostate and seminal vesicles. Uniform margins of 0.4, 0.8 and 1.2 cm were added around the clinical target volume to define three planning target volumes. Three well-established coplanar beam arrangements were simulated for all planning target volumes. Dose-volume histograms were calculated and quantitatively compared. Results. The mean dose (Dm) for PTVs ranged from 98.7 to 99.9%, with standard deviations ranging from 1.5 to 1.7%. Plan I appeared to be the best considering the Dm for the rectum, whereas Plan II appeared to be the best considering V95 (fraction of volume receiving a dose higher than 95% of the isocenter dose for the rectum). Plan III appeared to be the best considering the Dm and V95 for the bladder and also considering the Dm and V50 for the femur. Conclusions. This conceptual study suggested that the differences in shapes and volumes of planning target volume might be taken into consideration in an attempt to individually establish the optimum beam arrangements for three-dimensional conformal radiation therapy delivery in prostate cancer.en_US
dc.identifier.endpage277+285en_US
dc.identifier.issn1318-2099
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-31544474035en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage273en_US
dc.identifier.urihttps://hdl.handle.net/11616/91605
dc.identifier.volume39en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSciendoen_US
dc.relation.ispartofRadiology and Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProstatic neoplasms radiotherapyen_US
dc.subjectRadiotherapy, conformalen_US
dc.titleCorrelation of clinical target volume and the margins to define planning target volume with beam arrangements for three-dimensional conformal radiation therapy delivery for prostate canceren_US
dc.typeArticleen_US

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