Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma

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dc.contributor.authorGürünlüoğlu, Semra
dc.contributor.authorŞamdancı, Emine Türkmen
dc.contributor.authorArslan, Ahmet Kadir
dc.contributor.authorAkpolat, Nusret
dc.contributor.authorŞahin, Nurhan
dc.contributor.authorGökçe, Hasan
dc.date.accessioned2021-03-17T10:55:02Z
dc.date.available2021-03-17T10:55:02Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.descriptionDOI: https://doi.org/10.5455/annalsmedres.2020.06.578en_US
dc.description.abstractAbstract: Aim: Gastric carcinoma is the fourth most common carcinoma worldwide. The relationships established between the tumor morphology and the prognosis have not been very effective until recent times. Poorly Differentiated Clusters (PDCs); are structures those can be easily identified in H&E sections. A new grading system based on PDC count has been studied in colorectal carcinoma; and found to be associated with prognosis. We have aimed to investigate this concept in gastric carcinoma. Material and Methods: Our study included 80 cases, consisting of 16 females and 64 males having gastric carcinoma with intestinal morphology. For each case; conventional grade, PDC grade and prognostic parameters to be applied in the study were determined, and statistically compared. Results: Significant discrepancy was found between the two grading systems. PDC tumor grades were statistically related to; median metastatic lymph node counts, metastatic lymph node ratios, lymph node stages (pN) and the presence of perineural invasion. Conclusion: In stomach carcinoma; PDC grading system was found to be related to a significant part of the expected parameters and may have a prognostic value.en_US
dc.identifier.citationGÜRÜNLÜOĞLU S,ŞAMDANCI E. T,ARSLAN A. K,AKPOLAT N,ŞAHİN N,GÖKÇE H (2020). Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research, 27(8), 2022 - 2030. Doi: 10.5455/annalsmedres.2020.06.578en_US
dc.identifier.doi10.5455/annalsmedres.2020.06.578en_US
dc.identifier.endpage2030en_US
dc.identifier.issn2636-7688
dc.identifier.issue8en_US
dc.identifier.startpage2022en_US
dc.identifier.trdizinid383348en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.06.578
dc.identifier.urihttps://hdl.handle.net/11616/19573
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/383348
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePrognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinomaen_US
dc.typeArticleen_US

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