The Effect of Agoraphobia on Oxidative Stress in Panic Disorder

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dc.authoridTürköz, Yusuf/0000-0001-5401-0720
dc.authoridErdemli, Erman/0000-0003-4596-7525
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridKarlıdağ, Rifat/0000-0002-3650-0774
dc.authoridkartalcı, şükrü/0000-0003-2560-0355
dc.authorwosidTürköz, Yusuf/ABG-7931-2020
dc.authorwosidErdemli, Erman/ABI-8193-2020
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidKarlıdağ, Rifat/AAB-4281-2021
dc.authorwosidkarlıdağ, rıfat/AAB-4255-2021
dc.authorwosidkartalcı, şükrü/ABI-1106-2020
dc.contributor.authorGul, Lsil Gogcegoz
dc.contributor.authorKarlidag, Rifat
dc.contributor.authorCumurcu, Birgul Elbozan
dc.contributor.authorTurkoz, Yusuf
dc.contributor.authorKartalci, Sukru
dc.contributor.authorOzcan, A. Cemal
dc.contributor.authorErdemli, M. Erman
dc.date.accessioned2024-08-04T20:38:01Z
dc.date.available2024-08-04T20:38:01Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe aimed to investigate whether agoraphobia (A) in panic disorder (PD) has any effects on oxidative and anti-oxidative parameters. We measured total antioxidant capacity (TAG), paraoxonase (PUN), arylesterase (ARE) antioxidant and malondialdehyde (MDA) oxidant levels using blood samples from a total of 31 PD patients with A, 22 PD patients without A and 53 control group subjects. There was a significant difference between the TAG, PUN, ARE and MDA levels of the three groups consisting of PD with A, PD without A and the control group. The two-way comparison to clarify the group creating the difference showed that the TAG, PUN, and ARE antioxidants were significantly lower in the PD with A group compared to the control group while the MDA oxidant was significantly higher. There was no significant difference between the PD without A and control groups for TAG, PUN, ARE and MDA levels. We clearly demonstrated that the oxidative stress and damage to the anti-oxidative mechanism are significantly higher in the PD group with A. These findings suggest that oxidative/anti-oxidative mechanisms may play a more important role on the pathogenesis of PB with A.en_US
dc.description.sponsorshipInonu University Scientific Research Project Uniten_US
dc.description.sponsorshipThis study was supported by Inonu University Scientific Research Project Unit.en_US
dc.identifier.doi10.4306/pi.2013.10.4.317
dc.identifier.endpage325en_US
dc.identifier.issn1738-3684
dc.identifier.issn1976-3026
dc.identifier.issue4en_US
dc.identifier.pmid24474979en_US
dc.identifier.scopus2-s2.0-84892531472en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage317en_US
dc.identifier.urihttps://doi.org/10.4306/pi.2013.10.4.317
dc.identifier.urihttps://hdl.handle.net/11616/96322
dc.identifier.volume10en_US
dc.identifier.wosWOS:000329599900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Neuropsychiatric Assocen_US
dc.relation.ispartofPsychiatry Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAgoraphobiaen_US
dc.subjectFree radicalen_US
dc.subjectPanic disorderen_US
dc.subjectOxidative stressen_US
dc.subjectTotal antioxidant capacityen_US
dc.titleThe Effect of Agoraphobia on Oxidative Stress in Panic Disorderen_US
dc.typeReview Articleen_US

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