Dosimetric comparison of helical tomotherapy, intensity-modulated radiation therapy, volumetric-modulated arc therapy, and 3-dimensional conformal therapy for the treatment of T1N0 glottic cancer

Basit Öğe Kaydı
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridkaya pepele, eda/0000-0002-9193-0961
dc.authoridAltınok, Pelin/0000-0001-5970-6452
dc.authoridtemelli, oztun/0000-0003-3471-1284
dc.authorwosidEkici, Kemal/AAF-6505-2022
dc.authorwosidEkici, Kemal/AFJ-9488-2022
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidkaya pepele, eda/HGE-0700-2022
dc.authorwosidAltınok, Pelin/AAR-9359-2020
dc.authorwosidtemelli, Oztun/ABE-6986-2020
dc.contributor.authorEkici, Kemal
dc.contributor.authorPepele, Eda K.
dc.contributor.authorYaprak, Bahaddin
dc.contributor.authorTernelli, Oztun
dc.contributor.authorEraslan, Aysun F.
dc.contributor.authorKucuk, Nadir
dc.contributor.authorAltinok, Ayse Y.
dc.date.accessioned2024-08-04T20:42:52Z
dc.date.available2024-08-04T20:42:52Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractVarious radiotherapy planning methods for T1N0 laryngeal cancer have been proposed to decrease normal tissue toxicity. We compare helical tomotherapy (HT), linac-based intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), and 3-D conformal radiotherapy (3D-CRT) techniques for T1N0 laryngeal cancer. Overall, 10 patients with T1N0 laryngeal cancer were selected and evaluated. Furthermore, 10 radiotherapy treatment plans have been created for all 10 patients, including HT, IMRT, VMAT, and 3D-CRT. IMRT, VMAT, and HT plans vs 3D-CRT plans consistently provided superior planning target volume (PTV) coverage. Similar target coverage was observed between the 3 IMRT modalities. Compared with 3D-CRT, IMRT, HT, and VMAT significantly reduced the mean dose to the carotid arteries. VMAT resulted in the lowest mean dose to the submandibular and thyroid glands. Compared with 3D-CRT, IMRT, HT, and VMAT significantly increased the maximum dose to the spinal cord It was observed that the 3 IMRT modalities studied showed superior target coverage with less variation between each plan in comparison with 3D-CRT. The 3D-CRT plans performed better at the Dmax of the spinal cord. Clinical investigation is warranted to determine if these treatment approaches would translate into a reduction in radiation therapy-induced toxicities. (C) 2016 American Association of Medical Dosimetrists.en_US
dc.identifier.doi10.1016/j.meddos.2016.08.002
dc.identifier.endpage333en_US
dc.identifier.issn0958-3947
dc.identifier.issn1873-4022
dc.identifier.issue4en_US
dc.identifier.pmid27765542en_US
dc.identifier.scopus2-s2.0-85006069953en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage329en_US
dc.identifier.urihttps://doi.org/10.1016/j.meddos.2016.08.002
dc.identifier.urihttps://hdl.handle.net/11616/97631
dc.identifier.volume41en_US
dc.identifier.wosWOS:000389011500012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofMedical Dosimetryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLarynx canceren_US
dc.subjectHelical tomotherapyen_US
dc.subjectVolumetric arc therapyen_US
dc.subjectIntensity-modulated radiotherapyen_US
dc.titleDosimetric comparison of helical tomotherapy, intensity-modulated radiation therapy, volumetric-modulated arc therapy, and 3-dimensional conformal therapy for the treatment of T1N0 glottic canceren_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu