Seizures in Pediatric Patients With Liver Transplant and Efficacy of Levetiracetam

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dc.authoridARSLAN, MÜJGAN/0000-0002-0486-3431;
dc.authorwosidARSLAN, MÜJGAN/AAN-5584-2021
dc.authorwosidArslan, Müjgan/AAN-5580-2021
dc.contributor.authorKilic, Betuel
dc.contributor.authorGungor, Serdal
dc.contributor.authorArslan, Mujgan
dc.contributor.authorSelimoglu, Mukadder Ayse
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:43:13Z
dc.date.available2024-08-04T20:43:13Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the risk factors, clinical implications, and prognosis of new-onset seizures that occurred after pediatric liver transplantation, and to assess the efficacy of levetiracetam treatment. The clinical and laboratory data of liver transplanted 28 children who had seizures after liver transplantation and specifically of 18 children who received levetiracetam were analyzed retrospectively. Sixteen patients (88.9%) remained seizure-free and in 2 (11.1%), more than 50% reduction in seizures were detected with levetiracetam treatment. In conclusion, seizures are generally the most common complication by a spectrum of seizure types, and sometimes cause symptomatic epilepsy. The most common risk factors for seizures in transplant recipients is immunosuppressant toxicity. Currently, there isn't a specific treatment involving the transplant patient population. Levetiracetam may be preferable in pediatric patients as it's reliable for liver disease and has advantages in the treatment of postoperative seizures due to its intravenous usage.en_US
dc.identifier.doi10.1177/0883073817703502
dc.identifier.endpage745en_US
dc.identifier.issn0883-0738
dc.identifier.issn1708-8283
dc.identifier.issue8en_US
dc.identifier.pmid28420301en_US
dc.identifier.scopus2-s2.0-85021206673en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage740en_US
dc.identifier.urihttps://doi.org/10.1177/0883073817703502
dc.identifier.urihttps://hdl.handle.net/11616/97864
dc.identifier.volume32en_US
dc.identifier.wosWOS:000404044200007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal of Child Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectliver transplantationen_US
dc.subjectchildhooden_US
dc.subjectseizuresen_US
dc.subjectlevetiracetamen_US
dc.titleSeizures in Pediatric Patients With Liver Transplant and Efficacy of Levetiracetamen_US
dc.typeArticleen_US

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