The prevalence and molecular typing of enterotoxigenic Escherichia coli strains isolated from diarrheic stools in Malatya, Turkey

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dc.authoridIseri, latife/0000-0003-2598-9516
dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidDURMAZ, Rıza/HJH-4918-2023
dc.authorwosidÖzerol, İbrahim Halil/ABI-8015-2020
dc.authorwosidIseri, latife/B-6052-2015
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.contributor.authorOzerol, IH
dc.contributor.authorBayraktar, MR
dc.contributor.authorIseri, L
dc.contributor.authorOtlu, B
dc.contributor.authorDurmaz, R
dc.date.accessioned2024-08-04T20:15:02Z
dc.date.available2024-08-04T20:15:02Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study was performed from June 2002 to November 2003 year in Malatya, eastern Turkey. Stools of 172 diarrheic patients and 90 healthy controls were analysed for enterotoxigenic Escherichia coli (ETEC). Heat-labile (LT) and heat-stable (ST) toxins were investigated by passive latex agglutination and enzyme immunoassay, respectively. Nine ETEC strains were isolated from 172 diarrheic stools (5.2%). Seven of the ETEC strains (10.1%) were isolated from 69 children in the 0-5 year age group. Two of these pediatric isolates were ST positive (2.9%) and five were LT positive (7.2%). ETEC was not isolated in the 6-18 year age group. Two ST producing E. coli strains were detected in diarrheic adult patients (> 18 years). In the 90 controls, two ETEC strains were detected (2.2%). One of them was a IT producer (1.1%) and the other was a ST producer (1.1%). E. coli strains producing both toxins simultaneously were not observed. ETEC positivity was higher in the diarrheic group than in the control group but statistically not significant (p > 0.05). The rate of resistance among ETEC strains to cefuroxime axetil, ampicillin, piperacillin, and trimethoprim-sulfametboxazole was 72.7%, 54.5%, 45.5%, and 36.4%, respectively whereas the resistance rate to the same antibiotics in non-ETEC strains was 14%, 62%, 54%, and 66%, respectively. All ETEC isolates were intermediatelv resistant to cephalothin and fully susceptible to other antibiotics tested. Typing of the ETEC strains was done by arbitrary primed polymerase chain reaction (AP-PCR). Only two LT strains of the 11 typed strains had a unique profile. The remaining nine were mixed LT and ST strains and divided into two groups. The first group had three strains having a similarity coefficient ranging from 70-90%. The other one had six strains, five of them were similar and one was subtype isolate. It can be concluded that ETEC strains might be consider, ably important enteropathogens especially in pediatric patients in the 0-5 year age group. High clonal relation indicated that ETEC strains were epidemiologically related.en_US
dc.identifier.endpage243en_US
dc.identifier.issn1121-7138
dc.identifier.issue3en_US
dc.identifier.pmid16240696en_US
dc.identifier.scopus2-s2.0-25444446602en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage237en_US
dc.identifier.urihttps://hdl.handle.net/11616/94107
dc.identifier.volume28en_US
dc.identifier.wosWOS:000232227600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Int Srlen_US
dc.relation.ispartofNew Microbiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectenterotoxigenic Escherichia colien_US
dc.subjectETECen_US
dc.subjectdiarrheaen_US
dc.subjectantimicrobial susceptibilityen_US
dc.subjectmolecular typingen_US
dc.titleThe prevalence and molecular typing of enterotoxigenic Escherichia coli strains isolated from diarrheic stools in Malatya, Turkeyen_US
dc.typeArticleen_US

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