Comparison of the Effects of Ketamine and Propofol Combined with Remifentanil 1 ?g kg-1 Bolus on Hemodynamic Changes and Intubating Conditions during Anesthetic Induction

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dc.authorscopusid7003586739
dc.authorscopusid6701613323
dc.authorscopusid55898201200
dc.authorscopusid7004621949
dc.authorscopusid6603402358
dc.authorscopusid7004486274
dc.contributor.authorDemirbilek S.
dc.contributor.authorTo?al T.
dc.contributor.authorGülhaş N.
dc.contributor.authorÇiçek M.
dc.contributor.authorDo?an Z.
dc.contributor.authorErsoy M.O.
dc.date.accessioned2024-08-04T20:02:09Z
dc.date.available2024-08-04T20:02:09Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim of this study was to compare the effects of ketamine and propofol combined with remifentanil 1 ?g kg-1 bolus on hemodynamic changes and intubating conditions during anesthetic induction. After obtaining approval from the Ethics Committee and patient informed consent, 44 patients, ASA physical status I, aged 20-56 years, who scheduled for elective surgery, were divided into two groups randomly. After administration of a bolus dose of remifentanil 1 ?g kg-1, patients in group K (n=22) received ketamine 1-1.5 mg kg-1, group P (n=22) received propofol 1.5-2 mg kg-1. The trachea was intubated 3 minutes after administration of vecuronium 0.1 mg kg-1 in all patients. The quality of intubation was scored as perfect, good and poor. Anesthesia was maintained with sevoflurane 1-1.5 % and 50 % nitrous oxide in oxygen, and if necessary remifentanil 0.5 pg kg-1 was administered. Systolic blood pressure (SAP), diastolic blood pressure (DAP), mean arterial pressure (MAP) and heart rate (HR) were recorded before (control) and after induction, before and 1, 3 and 5 min after placement of the tracheal tube, 1 min after surgical incision and every 5 min up to 30 minutes. Until surgical incision, SAP, DAP, MAP and HR were higher in group K than group P. There were no significance between groups regarding intubation scores and additional remifentanil requirements. As a result, we concluded that 1 pg kg-1 bolus of remifentanil combined with ketamine during induction provides better hemodynamic stability, and similar intubating conditions, when comparing those of propofol-remifentanil induction.en_US
dc.identifier.endpage242en_US
dc.identifier.issn1304-0871
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-0142137327en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage237en_US
dc.identifier.urihttps://hdl.handle.net/11616/91441
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnesthetic inductionen_US
dc.subjectKetamineen_US
dc.subjectPropofolen_US
dc.subjectRemifentanilen_US
dc.subjectTracheal intubationen_US
dc.titleComparison of the Effects of Ketamine and Propofol Combined with Remifentanil 1 ?g kg-1 Bolus on Hemodynamic Changes and Intubating Conditions during Anesthetic Inductionen_US
dc.title.alternativeAnestezi İndüksiyonunda 1 ?g kg-1 Bolus Doz Remifentanil İle Birlikte Kullanilan Ketamin ve Propofolün Hemodinami ve Entübasyon Koşullarina Etkilerinin Karşilaş tirilmasien_US
dc.typeArticleen_US

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