CR3022 Antikoru ile Cihazdan Bağımsız Pratik Kağıt Tabanlı İmmünotest ile Direkt SARS CoV-2 Teşhisi
Küçük Resim Yok
Dosyalar
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Pandemia could be emerged at any time and resulted with death in the world. Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) caused the latest pandemia. Because of the absence of rapid diagnostic assays pandemia has surged in and caused the death of lots of people as SARS CoV-2 appeared at first time. Although reverse transcriptase polymerase chain reaction (RT-PCR) accepted as the most reliable test was used for the viral detection at first time, there are shortcomings including the need of educated personnel and difficulty of the usage of this test in undeveloped countries. For this reason, developing the rapid assays for direct recognition of virus is always eesential. Paper based immunoassays are significant among these assays and they are known as dot-blot assay (DBA). It is practical and easy to use since they are suitable for direct application of body fluids. Antibodies and aptamers are the most important reagents of diagnostic assays and it should be used having the high affinity of them. In this work, DBA was prepared by antibody-aptamer based sandwich assay and reported the suitibility of it for viral detection.
Açıklama
Anahtar Kelimeler
SARS CoV-2 Dot blot assay viral diagnosis paper assay
Kaynak
Erciyes Üniversitesi Fen Bilimleri Enstitüsü Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
3
Künye
DERİN, D. Ç. (2024). CR3022 Antikoru ile Cihazdan Bağımsız Pratik Kağıt Tabanlı İmmünotest ile Direkt SARS CoV-2 Teşhisi. Erciyes Üniversitesi Fen Bilimleri Enstitüsü Dergisi , 40(3), 528 - 534.
