Serum Fetuin-A Levels, QT Dispersion and P Dispersion in Dialysis Patients

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dc.authoridComert, Melda/0000-0002-7798-4349
dc.authoridAkaycan, Jülide/0000-0002-9174-6777
dc.authoridTaskapan, Mehmet Cagatay/0000-0002-5273-4909
dc.authoridulutas, ozkan/0000-0002-2155-8340
dc.authoridtaskapan, hulya/0000-0001-8736-4779
dc.authorwosidComert, Melda/ABH-5764-2020
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.authorwosidTaskapan, Mehmet Cagatay/ABI-7747-2020
dc.authorwosidulutas, ozkan/ABI-6332-2020
dc.authorwosidtaskapan, hulya/ABI-7737-2020
dc.contributor.authorTaskapan, Mehmet Cagatay
dc.contributor.authorTaskapan, Hulya
dc.contributor.authorComert, Melda
dc.contributor.authorTemel, Ismail
dc.contributor.authorYagmur, Julide
dc.contributor.authorUlutas, Ozkan
dc.date.accessioned2024-08-04T20:37:32Z
dc.date.available2024-08-04T20:37:32Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: This study aims to find association of fetuin-A with serum lipids, QT dispersion (QT-d), and P dispersion (P-d) in dialysis patients. Methods: Fetuin-A serum levels were assessed in 50 dialysis patients. Results: Serum fetuin-A levels were significantly associated with QT-d (r = 0.289, p = 0.044), P-d (r = 0.39, p = 0.005), total cholesterol (r = 0.526, p = 0.000), low-density lipoprotein cholesterol (LDL-C) (r = 0.456, p = 0.00), triglyceride (r = 0.360, p = 0.011) and highly sensitive C-reactive protein (hsCRP) (r = -0.347, p = 0.030). In step-wise multiple regression analysis including being on hemodialysis (HD), presence of diabetes mellitus (DM), total cholesterol, LDL-C, triglycerides, hsCRP, only total cholesterol (b = 0.419, p = 0.03), and hsCRP (b = -0.316, p = 0.03) proved to be independent predictors of serum fetuin-A levels. QT-d showed a linear correlation with total cholesterol (r = 0.309, p = 0.029), LDL-C (r = 0.304, p = 0.038), P-d (r = 0.390, p = 0.005), and fetuin-A levels (r = 0.289, p = 0.044). In multiple regression analyses, the independent predictor of QT-d was being on HD (b = -0.417, p = 0.004), whereas total cholesterol, LDL-C, presence of DM, serum fetuin-A levels, and P-d had no independent effect on corrected QT (QT-C). Being on HD and age were important determinants of P-d whereas presence of DM, total cholesterol, LDL-C, fetuin-A, and QT-d had no independent effect on P-d. Conclusions: Lower fetuin-A levels are associated with high hsCRP and low cholesterol levels in dialysis patients.en_US
dc.identifier.doi10.3109/0886022X.2013.768938
dc.identifier.endpage482en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue4en_US
dc.identifier.pmid23438291en_US
dc.identifier.scopus2-s2.0-84876388965en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage477en_US
dc.identifier.urihttps://doi.org/10.3109/0886022X.2013.768938
dc.identifier.urihttps://hdl.handle.net/11616/96012
dc.identifier.volume35en_US
dc.identifier.wosWOS:000317661200009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfetuin-Aen_US
dc.subjectQT dispersionen_US
dc.subjectP dispersionen_US
dc.subjectvascular calcificationen_US
dc.subjectdialysisen_US
dc.titleSerum Fetuin-A Levels, QT Dispersion and P Dispersion in Dialysis Patientsen_US
dc.typeArticleen_US

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