Left atrial volume and function in patients with white-coat hypertension assessed by real-time three-dimensional echocardiography
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
BackgroundWhite-coat hypertension (WCH) is a disease based on the disparity of a patient's blood pressure measurements between the physician's office and the patient's home environment. The aim of the present study is to evaluate the left atrial (LA) volume and functions in WCH.MethodsIn total, this study included 37 WCH (17 women, 20 men, mean age 48.45.7 years) and 30 healthy individuals (18 women, 20 men, mean age 47.97.5 years). All patients underwent real-time three-dimensional and comprehensive two-dimensional echocardiography (2DE) with tissue Doppler evaluation to estimate left atrial volumes and mechanical functions.ResultsLA diameters were significantly higher in the patients compared with the controls (37 +/- 2.8 vs. 35 +/- 3.1mm, P=0.017). LA total systolic volume and LA maximal volume were significantly higher in the patients. (41.1 +/- 6.9 vs. 35.5 +/- 3.7ml, P<0.001; 25.8 +/- 5.4 vs. 21.3 +/- 3.3ml, P<0.001, respectively). LA volume before LA contraction and LA active stroke volume were significantly higher in the patients with WCH than in the normotensives (24.4 +/- 6.3 vs. 20.9 +/- 2ml, P=0.002; 9.1 +/- 4.8 vs. 6.7 +/- 2.5ml, P=0.007, respectively). Moreover, the LA expansion index was significantly higher in the patients with WCH than in the normotensives (178.7 +/- 53.6 vs. 155.3 +/- 36.3, P=0.037). However, the total emptying volume fraction of the LA was similar between the two groups.ConclusionWe showed that LA structural functions and volumes were increased in the WCH group. Although increased LA volume has been observed in many diseases, structural changes in LA may be accepted as an early sign for clinical cardiac remodeling in patients with WCH, suggesting the necessity of early intervention for preventing clinical cardiovascular disease.
Açıklama
Anahtar Kelimeler
left atrial function, real-time three-dimensional echocardiography, white-coat hypertension
Kaynak
Blood Pressure Monitoring
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
21
Sayı
4
