Rhodium(I) complexes with N-heterocyclic carbene ligands: synthesis, biological properties and catalytic activity in the hydrosilylation of aromatic ketones

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dc.authoridGurbuz, Nevin/0000-0003-3201-3597
dc.authoridMansour, Lamjed/0000-0002-9415-9383
dc.authorwosidGurbuz, Nevin/A-3069-2016
dc.authorwosidMansour, Lamjed/U-3028-2017
dc.contributor.authorHamdi, Naceur
dc.contributor.authorSlimani, Ichraf
dc.contributor.authorMansour, Lamjed
dc.contributor.authorAlresheedi, Faisal
dc.contributor.authorOzdemir, Ismail
dc.contributor.authorGurbuz, Nevin
dc.date.accessioned2024-08-04T20:50:46Z
dc.date.available2024-08-04T20:50:46Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractNew rhodium(I) N-heterocyclic carbene (NHC) complexes 3a-f were synthesized in good yields by the reactions of rhodium dimer [Rh(OMe)(cycloocta-1,5-diene:COD)](2) with benzimidazolium salts 2a-f in tetrahydrofuran. All the complexes were characterized by IR, H-1-NMR, and C-13-NMR spectroscopy, DART-TOF mass spectrometry (for 3b, 3d and 3f) and elemental analysis. All complexes were used as catalysts in the hydrosilylation of acetophenone derivatives with triethylsilane at 80 degrees C for 1 h. These Rh(I) NHC showed good catalytic performance for the hydrosilylation of acetophenone derivatives by using 1 mol % of the rhodium complexes. In addition the new rhodium(I) NHC complexes were tested against MCF7 and MDA-MB-231 cancer cells, Micrococcus luteus LB 14110, Listeria monocytogenes ATCC 19117, Salmonella Typhimurium ATCC 14028, Staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa and Candida albicans microorganisms. The synthesized rhodium(I) NHC complex 3f was found the most active against MCF7 cancer cells (half-growth inhibition concentration (IC50) = 0.3 mu g mL(-1)), as well as the most potent antimicrobial against L. monocytogenes ATCC 19117 (inhibition zone (IZ) = 29 mm). Moreover, the antioxidant activity determination of these complexes was studied with the DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) and compared with gallic acid and butylated hydroxytoluene.en_US
dc.description.sponsorshipQassim University [10091-alrasscac-bs-2020-1-3-I]en_US
dc.description.sponsorshipThe authors gratefully acknowledge Qassim University, represented by the Deanship of Scientific Research, on the financial support for this research under the number (10091-alrasscac-bs-2020-1-3-I) during the academic year 1442 AH / 2020 AD.en_US
dc.identifier.doi10.1080/00958972.2021.1992400
dc.identifier.endpage2579en_US
dc.identifier.issn0095-8972
dc.identifier.issn1029-0389
dc.identifier.issue15en_US
dc.identifier.scopus2-s2.0-85117293700en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage2558en_US
dc.identifier.urihttps://doi.org/10.1080/00958972.2021.1992400
dc.identifier.urihttps://hdl.handle.net/11616/100271
dc.identifier.volume74en_US
dc.identifier.wosWOS:000709212300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Coordination Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRhodium(I) N-heterocyclic carbene complexesen_US
dc.subjectbenzimidazolium saltsen_US
dc.subjecthydrosilylationen_US
dc.subjectbiological propertiesen_US
dc.subjectDART-TOF mass spectrometryen_US
dc.titleRhodium(I) complexes with N-heterocyclic carbene ligands: synthesis, biological properties and catalytic activity in the hydrosilylation of aromatic ketonesen_US
dc.typeArticleen_US

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