Interactive web-based software for evaluating diagnostic tests and roc curve analyses in health sciences

dc.contributor.authorYasar, Seyma
dc.contributor.authorYagin, Fatma Hilal
dc.contributor.authorArslan, Ahmet Kadir
dc.contributor.authorÇolak, Cemil
dc.contributor.authorYoloğlu, Saim
dc.date.accessioned2022-02-08T08:18:26Z
dc.date.available2022-02-08T08:18:26Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract: Aim: This study aims to develop web-based and user-friendly DTROC software in which clinicians and researchers can perform twoand three-dimensional receiver operating characteristic (ROC) curve analyses and calculate diagnostic test performance metrics. Materials and Methods: An illustrative example was presented to implement two- and three-dimensional ROC analyses in medicine. As a case study, three-dimensional ROC analysis in DTROC was applied to the ktemp variable (measurements on the neuropsychometric test for “temporal factor”) in the open-access data set named "AL” (Alzheimer's disease neuropsychometric marker dataset). DTROC web-based software was developed using “plotly”, “pROC”, “dplyr”, “shiny”, “shinydashboard”, “rhandsontable”, “shinyBS”, “DT”, “epiR”, “DiagTest3Grp”, and "the “shiny" libraries. Results: The developed web-based DTROC software allows clinicians and researchers to analyze two and three-dimensional ROC analyzes, ROC curve comparisons, optimum cut-off calculations, required sample size estimation for diagnosis, and calculate metrics for two/more than two-class diagnostic tests without any programming language knowledge or theoretical background about the analyzes mentioned above. When the results for the ktemp variable in the AL data set used in practice were examined, the volume under the surface was found to be 0.77. According to the application results in DTROC Three-dimensional ROC analysis, it can be said that the ktemp variable has a distinguishing feature in detecting AL. Conclusion: All the comprehensive features of DTROC can be accessed free of charge through a graphical user interface that makes the analysis process very easy for users and automates the analysis process. With all these features, DTROC provides much more comprehensive features and various applications than commercial and free software to achieve two/three-dimensional ROC analyses and calculate diagnostic test metrics for two / more classes.en_US
dc.identifier.citationYASAR S,YAGİN F. H,ARSLAN A. K,COLAK C,YOLOGLU S (2021). Interactive web-based software for evaluating diagnostic tests and roc curve analyses in health sciences. Annals of Medical Research, 28(11), 2012 - 2018.en_US
dc.identifier.doi10.5455/annalsmedres.2021.01.103en_US
dc.identifier.endpage2018en_US
dc.identifier.issn2636-7688
dc.identifier.issue11en_US
dc.identifier.startpage2012en_US
dc.identifier.trdizinid482763en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2021.01.103
dc.identifier.urihttps://hdl.handle.net/11616/46811
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/482763
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleInteractive web-based software for evaluating diagnostic tests and roc curve analyses in health sciencesen_US
dc.typeArticleen_US

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