An interactive web application for propensity score matching with R shiny; example of thrombophilia

dc.contributor.authorDemir, Emre
dc.contributor.authorKose, Serdal Kenan
dc.contributor.authorAkmese, Omer Faruk
dc.contributor.authorYildirim, Engin
dc.date.accessioned2022-03-08T14:28:19Z
dc.date.available2022-03-08T14:28:19Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The aim of this study was to develop a new web-based R Shiny package that calculates propensity score using many algorithms such as logistic regression, machine learning, and performs matching analysis with balance evaluation. In addition, it was aimed to explain the process of matching analysis on a real data set by comparing the number of live births between those with methylenetetrahydrofolate reductase (MTHFR) homozygous mutations and those without mutations in women hospitalized due to abortion in the gynecology and obstetrics clinic.Material and Methods: The web-based application was developed using R shiny. The “matchIt” library was used for matching analysis and PS prediction. The “cobalt” library was used to evaluate balance and generate plots.Results: The abortion variable, which was statistically significantly different in the groups before matching (p=0.010), was similar in the groups after matching (p=0.743). In addition, when the descriptive statistics and p values of the other variables were examined, it was seen that almost full balance was achieved after matching and the confounder variables were similar distributed in groups. After matching analysis, it was determined that the result variable “livebirths” did not show statistically significant difference in the groups (p=0.864).Conclusion: In this study, we developed an interactive web application for matching analysis based on propensity score. It is thought that this application will facilitate the studies of the researchers.en_US
dc.identifier.citationDemir, E., Kenan Kose, S., Faruk Akmese, O., & Yildirim, E. (2021). An interactive web application for propensity score matching with R shiny; example of thrombophilia . Annals of Medical Researchen_US
dc.identifier.urihttps://hdl.handle.net/11616/54821
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAn interactive web application for propensity score matching with R shiny; example of thrombophiliaen_US
dc.typeArticleen_US

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