Biostimulatory Effects of Diode Laser and Ozone on Wound Healing in Rats

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dc.authoridYolcu, Ümit/0000-0001-7312-2867
dc.authoridGuler, Cigdem/0000-0002-2581-9050
dc.authoriddemir, pınar/0000-0003-2030-5429
dc.authoridCakir, Ebru/0000-0001-7959-3491
dc.authorwosidYolcu, Ümit/ABH-6916-2020
dc.authorwosidalan, hilal/ABH-9301-2020
dc.authorwosidGuler, Cigdem/KPA-0490-2024
dc.authorwosiddemir, pınar/AAE-7027-2020
dc.contributor.authorAlan, Hilal
dc.contributor.authorGuler, Cigdem
dc.contributor.authorYolcu, Umit
dc.contributor.authorKoparal, Mahmut
dc.contributor.authorCakir, Ebru
dc.contributor.authorDemir, Pinar
dc.date.accessioned2024-08-04T20:10:31Z
dc.date.available2024-08-04T20:10:31Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Diode laser and ozone can be used to healing of skin wounds. The aim of this study is to evaluate the biostimulatory effects of diode laser and ozone on the healing of sutured skin wounds in rats. Materials and Methods: In this study, 21 adult males Wistar albino rats were used. Three 1-cm-longs, full-thickness incisions were applied to the back of each animal and closed with sutures. Diode laser treatment, irrigation with 0.9% saline solution and ozone therapy was applied to the wounds through 7 days. Animals were euthanized on the 3rd, 7th, and 14th days after treatment, and all wounds were surgically removed for histopathological evaluation. Results: According to histological results, a statistically significant difference was found among the three treatment methods in acute inflammatory reactions on 3rd day (p<0.05). Ozone treatment reduced the intensity of acute inflammatory reactions by the 3rd day (p<0.05). In addition, a statistically significant difference was found between the follow-up periods in all treatment groups for fibrosis (p<0.01). Conclusion: It was found that ozone treatment was more effective when compared to the other treatments for reducing the intensity of acute inflammatory reactions on the healing of sutured skin wounds.en_US
dc.identifier.doi10.4274/meandros.97269
dc.identifier.endpage167en_US
dc.identifier.issn2149-9063
dc.identifier.issue2en_US
dc.identifier.startpage160en_US
dc.identifier.trdizinid306130en_US
dc.identifier.urihttps://doi.org/10.4274/meandros.97269
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/306130
dc.identifier.urihttps://hdl.handle.net/11616/92817
dc.identifier.volume19en_US
dc.identifier.wosWOS:000441983900009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofMeandros Medical and Dental Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOzoneen_US
dc.subjectdiode laseren_US
dc.subjectwound healingen_US
dc.subjectraten_US
dc.subjecttherapyen_US
dc.subjectsoft tissueen_US
dc.titleBiostimulatory Effects of Diode Laser and Ozone on Wound Healing in Ratsen_US
dc.typeArticleen_US

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