Increased Aqueous Humor Symmetric Dimethylarginine Level in Patients with Primary Open Angle Glaucoma

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dc.authoridBozgul, Pembegul/0000-0002-9427-3610
dc.authoridÖzyalın, Fatma/0000-0001-6486-6389
dc.authoridözyalın, fatma/0000-0001-6486-6389
dc.authoridTürköz, Yusuf/0000-0001-5401-0720
dc.authorwosiddikci, seyhan/A-3311-2019
dc.authorwosidBozgul, Pembegul/AAQ-4951-2020
dc.authorwosidÖzyalın, Fatma/ABC-7193-2020
dc.authorwosidözyalın, fatma/ABA-5258-2020
dc.authorwosidTürköz, Yusuf/ABG-7931-2020
dc.contributor.authorFirat, Penpe Gul
dc.contributor.authorDemirel, Ersan Ersin
dc.contributor.authorDemirel, Soner
dc.contributor.authorDikci, Seyhan
dc.contributor.authorTurkoz, Yusuf
dc.contributor.authorOzyalin, Fatma
dc.date.accessioned2024-08-04T20:46:00Z
dc.date.available2024-08-04T20:46:00Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To evaluate the asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and L-arginine (L-Arg) levels both in plasma and aqueous humor of primary open angle glaucoma (POAG) patients and matched controls.Patients and Methods: 25 primary open angle glaucoma patients and 42 control cases with senile cataract were included in the study. Plasma and aqueous humor ADMA, SDMA and L-Arg levels of the participants were measured by using liquid chromatography-tandem mass spectrometry.Results: A significant increase in aqueous humor SDMA level was detected in POAG patients compared with controls (p =0.0115). No significant difference was detected in plasma and aqueous humor ADMA, L-Arg levels.Conclusion: The aqueous humor levels of SDMA are found to be associated with POAG. The result of this current study supports the role of nitric oxide pathway in glaucoma.en_US
dc.description.sponsorshipInonu University Scientific Research Projecten_US
dc.description.sponsorshipCurrent study was supported by Inonu University Scientific Research Project.en_US
dc.identifier.doi10.1080/02713683.2019.1578378
dc.identifier.endpage622en_US
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue6en_US
dc.identifier.pmid30707048en_US
dc.identifier.scopus2-s2.0-85067106560en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage619en_US
dc.identifier.urihttps://doi.org/10.1080/02713683.2019.1578378
dc.identifier.urihttps://hdl.handle.net/11616/98827
dc.identifier.volume44en_US
dc.identifier.wosWOS:000471943300007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlaucomaen_US
dc.subjectasymmetric dimethylarginineen_US
dc.subjectsymmetric dimethylarginineen_US
dc.subjectL-arginineen_US
dc.titleIncreased Aqueous Humor Symmetric Dimethylarginine Level in Patients with Primary Open Angle Glaucomaen_US
dc.typeArticleen_US

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