Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study

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dc.contributor.authorUysal, Mukremin
dc.contributor.authorSaglam, Sezer
dc.contributor.authorBeypinar, Ismail
dc.contributor.authorSaglam, Esra Kaytan
dc.contributor.authorMammadov, Elkhan
dc.contributor.authorOcak, Birol
dc.contributor.authorAybi, Ozge
dc.date.accessioned2026-04-04T13:33:35Z
dc.date.available2026-04-04T13:33:35Z
dc.date.issued2026
dc.departmentİnönü Üniversitesi
dc.description.abstractThe goal of this study was to look at the long-term survival outcomes and clinical characteristics of stage II/III locally advanced rectal cancer (LARC) patients who acquired pathological complete response (pCR) following neoadjuvant chemoradiotherapy (NCRT). The clinicopathological characteristics and treatment details of 277 LARC patients with pCR, relapse-free survival (RFS), overall survival (OS), and locoregional and systemic recurrence rates, were assessed. The 5-year RFS and OS rates were 85.6% and 90.9%. The rates of local and systemic recurrence were 3.6% and 7.9%. Our study confirmed the favorable results in survival in patients with LARC who achieved pCR
dc.identifier.doi10.1080/07357907.2025.2595536
dc.identifier.endpage135
dc.identifier.issn0735-7907
dc.identifier.issn1532-4192
dc.identifier.issue2
dc.identifier.pmid41347635
dc.identifier.scopus2-s2.0-105024909531
dc.identifier.scopusqualityQ3
dc.identifier.startpage127
dc.identifier.urihttps://doi.org/10.1080/07357907.2025.2595536
dc.identifier.urihttps://hdl.handle.net/11616/109265
dc.identifier.volume44
dc.identifier.wosWOS:001631349200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCancer Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250329
dc.subjectDisease-free survival
dc.subjectLocal recurrence
dc.subjectLocal advanced rectal cancer
dc.subjectNeoadjuvant chemoradiation
dc.subjectPathological complete response
dc.subjectOverall survival
dc.subjectSurgical outcome
dc.titleLong-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study
dc.typeArticle

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