Serum and hair trace element levels in patients with epilepsy and healthy subjects: does the antiepileptic therapy affect the element concentrations of hair?

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dc.authorwosidUz, Efkan/B-2943-2016
dc.contributor.authorIlhan, A
dc.contributor.authorUz, E
dc.contributor.authorKali, S
dc.contributor.authorVar, A
dc.contributor.authorAkyol, O
dc.date.accessioned2024-08-04T20:12:00Z
dc.date.available2024-08-04T20:12:00Z
dc.date.issued1999
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, hair magnesium (Mg), zinc (Zn), copper (Cu), and manganese (Mn) levels, and serum Zn and Mg levels were measured by atomic absorption spectrophotometer in patients with epilepsy (n = 33) and healthy subjects (n = 21), and results obtained were statistically compared. The mean hair Cu, Mg, and Zn levels of epileptic patients were significantly lower than the levels of control subjects. There was no significant difference between epileptic patients and control subjects in respect to the mean Mn levels. Mean serum Mg levels in epileptic patients showed significant difference, but serum Zn levels were similar among both groups. When the effects of anticonvulsant therapy on Cu, Zn, Mn, and Mg in the hair, and Mg and Zn in the serum were analyzed in epileptics, there was no significant difference between the patients with or without therapy. Likewise, the mean trace element levels in epileptics showed no significant difference according to the type of antiepileptic drug and seizure, and gender. We suggest that the changed element status (Zn, Mg, and Cu) in hair may play an indicator role in the diagnosis of epileptic patients, fur J Neurol 6:705-709 (C) 1999 Lippincott Williams & Wilkins.en_US
dc.identifier.doi10.1046/j.1468-1331.1999.t01-1-660705.x
dc.identifier.endpage709en_US
dc.identifier.issn1351-5101
dc.identifier.issn1468-1331
dc.identifier.issue6en_US
dc.identifier.pmid10529759en_US
dc.identifier.scopus2-s2.0-0032763131en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage705en_US
dc.identifier.urihttps://doi.org/10.1046/j.1468-1331.1999.t01-1-660705.x
dc.identifier.urihttps://hdl.handle.net/11616/93153
dc.identifier.volume6en_US
dc.identifier.wosWOS:000083952700011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEuropean Journal of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectepilepsyen_US
dc.subjecthairen_US
dc.subjectserumen_US
dc.subjectcopperen_US
dc.subjectzincen_US
dc.subjectmagnesiumen_US
dc.subjectmanganeseen_US
dc.titleSerum and hair trace element levels in patients with epilepsy and healthy subjects: does the antiepileptic therapy affect the element concentrations of hair?en_US
dc.typeArticleen_US

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