Epidemiology of Pemphigus in Turkey: One-year Prospective Study of 220 Cases

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dc.authoridOdyakmaz Demirsoy, Evren/0000-0002-8120-9548
dc.authoridDurdu, Murat/0000-0003-1247-3932
dc.authoridOnsun, Nahide/0000-0001-6259-0219
dc.authoridDursun, Recep/0000-0002-1279-574X
dc.authoridBaskan, Emel Bulbul/0000-0002-0144-3263
dc.authoridErdem, Cengizhan/0000-0002-9312-5683
dc.authoridAktan, Sebnem/0000-0002-0201-4663
dc.authorwosidtopal, suhan g günaştı/U-3194-2018
dc.authorwosidSavk, Ekin/AAC-4126-2021
dc.authorwosidOdyakmaz Demirsoy, Evren/AAB-7136-2020
dc.authorwosidDilek, Nursel/AAK-5298-2021
dc.authorwosidKundakcı, Nihal/AAZ-6690-2020
dc.authorwosidDurdu, Murat/H-9068-2019
dc.authorwosidOnsun, Nahide/AAB-4951-2022
dc.contributor.authorYayli, Savas
dc.contributor.authorHarman, Mehmet
dc.contributor.authorBaskan, Emel Bulbul
dc.contributor.authorKarakas, Ayse Akman
dc.contributor.authorGenc, Yeser
dc.contributor.authorTurk, Bengu Gerceker
dc.contributor.authorDemirsoy, Evren Odyakmaz
dc.date.accessioned2024-08-04T20:44:05Z
dc.date.available2024-08-04T20:44:05Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. All patients newly diagnosed with pemphigus between June 2013 and June 2014 were prospectively enrolled in 33 dermatology departments in 20 different provinces from all seven regions of Turkey. Disease parameters including demography and clinical findings were recorded. A total of 220 patients were diagnosed with pemphigus during the 1-year period, with an annual incidence of 4.7 per million people in Turkey. Patients were predominantly women, with a male to female ratio of 1:1.41. The mean age at onset was 48.9 years. Pemphigus vulgaris (PV) was the commonest clinical subtype (n= 192; 87.3%), followed by pemphigus foliaceus (n= 21; 9.6%). The most common clinical subtype of PV was the mucocutaneous type (n= 83; 43.2%). The mean Pemphigus Disease Area Index was 28.14 +/- 22.21 (mean +/- Standard Deviation). The incidence rate of pemphigus in Turkey is similar to the countries of South-East Europe, higher than those reported for the Central and Northern European countries and lower than the countries around the Mediterranean Sea and Iran. Pemphigus is more frequent in middle-aged people and is more common in women. The most frequent subtype was PV, with a 9-fold higher incidence than pemphigus foliaceus.en_US
dc.identifier.endpage188en_US
dc.identifier.issn1330-027X
dc.identifier.issn1847-6538
dc.identifier.issue3en_US
dc.identifier.pmid29252169en_US
dc.identifier.scopus2-s2.0-85032013337en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage181en_US
dc.identifier.urihttps://hdl.handle.net/11616/98004
dc.identifier.volume25en_US
dc.identifier.wosWOS:000413524200001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCroation Dermatovenerological Socen_US
dc.relation.ispartofActa Dermatovenerologica Croaticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpemphigusen_US
dc.subjectepidemiologyen_US
dc.titleEpidemiology of Pemphigus in Turkey: One-year Prospective Study of 220 Casesen_US
dc.typeArticleen_US

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