Evaluation of contrast nephropathy in percutaneous treatment of chronic total occlusions
Küçük Resim Yok
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Akademiai Kiado Zrt
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Contrast-induced nephropathy (CIN) is a leading cause of morbidity and mortality in patients undergoing percutaneous coronary intervention (PCI). Chronic total occlusions (CTO) are frequently observed among patients undergoing coronary angiography. Methods: A total of 128 CTO patients were included. Mehran score, lesion characteristics, interventional procedure, serological specimens and devices were recorded. The first group was administered with 1 ml . kg(-1) . h(-1) saline (0.9% NaCl) infusion that started 12 h before the procedure and continued 12 h post procedure as recommended by the guidelines. The second group was administered with saline infusion of 12 ml . kg(-1) . h(-1) only during CTO-PCI procedure, which is called as intensive infusion. Results: CIN development was similar in two groups (four patients in standard hydration group and five patients in intensive hydration group). The amount of saline was significantly higher in the standard group (1,767 +/- 192.2 vs. 1,043.6 +/- 375; p < 0.001). Patients with higher creatinine levels prior to PCI had a higher rate of CIN development after procedure. Interestingly, age, left ventricular ejection fraction, and diabetes mellitus independently predicted CIN. Conclusion: Intensive hydration administration appears to be an effective and cost-effective method in CTO-PCI patients, especially in patients without left ventricular function failure.
Açıklama
Anahtar Kelimeler
chronic total occlusions, contrast-induced nephropathy, hydration, percutaneous coronary intervention, saline infusion
Kaynak
Interventional Medicine and Applied Science
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
11
Sayı
2
