Evaluation of clinical characteristics and outcomes of postoperative infections in living liver donors

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridKose, Adem/0000-0002-1853-1243
dc.authoridtoplu, sibel altunışık/0000-0002-2915-4666
dc.authoridDuman, Yucel/0000-0002-9090-2096
dc.authoridcolak, yusuf ziya/0000-0002-8729-8705
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidKose, Adem/AAD-1226-2020
dc.authorwosidtoplu, sibel altunışık/ABH-5816-2020
dc.authorwosidDuman, Yucel/AAU-6221-2020
dc.authorwosidYaşar, Şeyma/ABI-8055-2020
dc.authorwosidcolak, yusuf ziya/ABH-3032-2020
dc.contributor.authorKose, Adem
dc.contributor.authorAltunisik Toplu, Sibel
dc.contributor.authorAkbulut, Sami
dc.contributor.authorYasar, Seyma
dc.contributor.authorSarici, Kemal Baris
dc.contributor.authorDuman, Yucel
dc.contributor.authorKutlu, Ramazan
dc.date.accessioned2024-08-04T20:50:15Z
dc.date.available2024-08-04T20:50:15Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim To analyze developing infections after living donor hepatectomy (LDH) in living liver donors (LLDs). Methods Demographic and clinical characteristics of 1106 LLDs were retrospectively analyzed in terms of whether postoperative infection development. Therefore, LLDs were divided into two groups: with (n = 190) and without (n = 916) antimicrobial agent use. Results The median age was 29.5 (min-max: 18-55). A total of 257 (23.2%) infection attacks (min-max: 1-8) was developed in 190 (17.2%) LLDs. The patients with the infection that were longer intensive care unit (ICU) and hospital stays, higher hospital admissions, emergency transplantation, invasive procedures for ERCP, PTC biloma, and abscess drainage, and the presence of relaparatomies and transcystic catheters. Infection attacks are derived from a 58.3% hepatobiliary system, 13.2% urinary system, 6.6% surgical site, and 5.8% respiratory system. The most common onset symptoms were fever, abdominal pain, nausea, and vomiting. A total of 125 positive results was detected from 77 patients with culture positivity. The most detected microorganisms from the cultures taken are Extended-Spectrum beta-lactamases (ESBL) producing Klebsiella pneumonia (16.8%) and Escherichia coli (16%), Methicillin-Resistant Staphylococcus aureus [(MRSA) (9.6%)], Methicillin-susceptible S aureus [(MSSA) (9.6%)], and Pseudomonas aeruginosa (8.8%), respectively. The average number of ICU hospitalization days was 3 +/- 2 (min 1-max 30, IQR:1) and hospitalization days was 14 +/- 12 (min 3-max 138, IQR: 8). All infection attacks were successfully treated. No patients died because of infection or another surgical complication. Conclusion Infections commonly observed infected biloma, cholangitis, and abscess arising from the biliary system and other nosocomial infections are the feared complications in LLDs. These infections should be managed multidisciplinary without delay and carefully.en_US
dc.identifier.doi10.1111/ijcp.14324
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue8en_US
dc.identifier.pmid33960083en_US
dc.identifier.scopus2-s2.0-85106290449en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14324
dc.identifier.urihttps://hdl.handle.net/11616/99943
dc.identifier.volume75en_US
dc.identifier.wosWOS:000652557500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiliary Complicationsen_US
dc.subjectTransplantationen_US
dc.subjectLobectomyen_US
dc.titleEvaluation of clinical characteristics and outcomes of postoperative infections in living liver donorsen_US
dc.typeArticleen_US

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