HaNDL Syndrome Presenting During Pregnancy: A Case Report and Review of the Literature

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dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authorwosidKamisli, Ozden/JVZ-0145-2024
dc.authorwosidKamisli, Ozden/AAA-6553-2020
dc.contributor.authorKablan, Yuksel
dc.contributor.authorKamisli, Ozden
dc.contributor.authorCelik, Hamit
dc.date.accessioned2024-08-04T20:39:53Z
dc.date.available2024-08-04T20:39:53Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHeadache associated with neurological deficits and cerebrospinal fluid lymphocytosis (HaNDL) is a self-limiting syndrome characterized by sudden-onset headache with a temporary neurological deficit and cerebrospinal fluid (CSF) lymphocytosis. We aimed to disscus a case of HaNDL syndrome presenting during pregnancy with relevant literature. A 20-year-old female presented with a 5-day history of severe, bilateral throbbing headache accompanied by nausea, vomiting, and phonophobia. Approximately 2 days after the pain developed, she became acutely confused for less than 90 minutes. Two days after this episode, she experienced another confusional state and left hemiparesis. There were no symptoms consistent with meningoencephalitis. She was in her 11th week of pregnancy. A neurologic examination showed confusion, bilateral papilledema, and mild left hemiparesis. The neuroradiological examination was normal. The cerebrospinal fluid revealed lymphocytic pleocytosis, mildly elevated protein, and increased opening pressure. She recovered completely after 8 days. The precise etiology of HaNDL is unknown, although an inflammatory or infectious origin and autoimmune factors have been proposed. Moreover, the risk factors and medical conditions associated with HaNDL are also unknown. It is difficult to determine whether the pregnancy was coincidental or associated in this case. We believe that comprehensive studies are needed to clarify the risk factors and medical conditions associated with HaNDL.en_US
dc.identifier.doi10.4274/tnd.92489
dc.identifier.endpage94en_US
dc.identifier.issn1301-062X
dc.identifier.issn1309-2545
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84908202691en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.4274/tnd.92489
dc.identifier.urihttps://hdl.handle.net/11616/96575
dc.identifier.volume20en_US
dc.identifier.wosWOS:000217548800007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Neurological Socen_US
dc.relation.ispartofTurkish Journal of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHaNDL syndromeen_US
dc.subjectpregnancyen_US
dc.subjectconfusionen_US
dc.subjectbilateral papilledemaen_US
dc.titleHaNDL Syndrome Presenting During Pregnancy: A Case Report and Review of the Literatureen_US
dc.typeArticleen_US

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