Short-term effect of tibolone on C-reactive protein in hypertensive postmenopausal women

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dc.authoridİmadoğlu Yetkin, Gülay/0000-0002-6115-3583
dc.authoridEngin-Ustun, Yaprak/0000-0002-1011-3848
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authorwosidÜstün, Yusuf/AAC-2674-2020
dc.authorwosidUstun, Yaprak/KFQ-9767-2024
dc.authorwosidİmadoğlu Yetkin, Gülay/AAO-2547-2020
dc.contributor.authorEngin-Uestuen, Yaprak
dc.contributor.authorUestuen, Yusuf
dc.contributor.authorTuerkcueoglu, Ilgin
dc.contributor.authorMeydanli, M. Mutlu
dc.contributor.authorKafkasgh, Ayse
dc.contributor.authorYetkin, Guelay
dc.date.accessioned2024-08-04T20:31:07Z
dc.date.available2024-08-04T20:31:07Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo evaluate the effects of tibolone on the serum C-reactive protein (CRP) in hypertensive postmenopausal women. We enrolled 45 postmenopausal patients with hypertension and 17 normotensive postmenopausal women. Inclusion criteria were surgical menopause, the presence of vasomotor symptoms, and normal mammogram within 1 year, the absence of documented coronary artery disease, and normal electrocardiography. Forty hypertensive women and 17 normotensive women completed the 3-month period. Twenty-one hypertensive women received tibolone, whereas 19 served as control. At baseline and at 3 months, blood lipids and CRP were evaluated. Changes in lipid profile and CRP in the hypertensive and normotensive control groups during 3 months were not statistically significant. Total cholesterol levels decreased significantly after 3 months of tibolone treatment. A significant increase in CRP values was observed in the tibolone group (p = 0.001). This trial demonstrated that tibolone treatment induced a significant increase in CRP and a significant decrease in total cholesterol in postmenopausal hypertensive women.en_US
dc.identifier.doi10.1007/s00404-008-0712-6
dc.identifier.endpage309en_US
dc.identifier.issn0932-0067
dc.identifier.issn1432-0711
dc.identifier.issue3en_US
dc.identifier.pmid18584186en_US
dc.identifier.scopus2-s2.0-58849099920en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-008-0712-6
dc.identifier.urihttps://hdl.handle.net/11616/94739
dc.identifier.volume279en_US
dc.identifier.wosWOS:000262784600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMenopauseen_US
dc.subjectHypertensionen_US
dc.subjectTiboloneen_US
dc.subjectC-reactive proteinen_US
dc.titleShort-term effect of tibolone on C-reactive protein in hypertensive postmenopausal womenen_US
dc.typeArticleen_US

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