In vitro callus propagation and antibacterial activities of callus an edible endemic and medicinal plant Scutellaria orientalis L. Subsp. bicolor

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dc.authorscopusid55944950400
dc.authorscopusid36439498600
dc.authorscopusid6602206186
dc.contributor.authorOzdemir F.A.
dc.contributor.authorKilic O.
dc.contributor.authorAtalan E.
dc.date.accessioned2024-08-04T20:00:49Z
dc.date.available2024-08-04T20:00:49Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPlants are a stupendous source for exploration of new medicinal products for drug development. Today several drugs used to treat many diseases are simply synthetic modifications or copies of naturally obtained plant substances or extracts. Medicinal plants offer best source to obtain a variety of new drugs; and new plants need to be investigated for their potential use against various microorganisms including bacteria. Scutellaria orientalis subsp. bicolor in the Lamiaceae (mint) family, is an endemic plant species that grows widely on abondoned lands at altitude of 1000-2800 meters in Eastern Anatolia. The plant or extracts are popularly used in preparation of various traditional medicines to treat many diseases including stress, breast and ovarian cancers; however there is need to establish validity of these methodologies scientifically as plant tissue culture techniques could serve as an alternative way to produce them. This study aimed to documents crude callus extracts from hypocotyl explants obtained from 17 days old plantlets of Scutellaria orientalis subsp. bicolor for antibacterial activities. Research findings clearly showed inhibition of growth of Staphylococcus aureus COWAN 1 and Bacillus subtilis var. Niger ATCC 10 in the extracts determined by disc diffusion methodology. Antibacterial activity was evaluated by measuring zone diameters in mm. No antibacterial activities were detected in control group. The hexane, acetone and methanol extracts of S. orientalis subsp. bicolor calli exhibited inhibitory action against both bacterial strains. Moreover, callus extracts showed less anti bacterial activities on calli developed on MS medium containing NAA compared to calli obtained on MS medium containing BAP. Furthermore, the results confirmed inhibitory effects of increased BAP concentrations on callus weight, size and quantity of extracts. Moreover, methanol extracts showed more antibacterial activity compared to acetone and hexane extracts. Better knowledge about antibacterial activities of this endemic plant sub species could be highly useful for understanding ways for cheap, commercial production of these extracts at extensive level under controlled conditions. © Mattioli 1885.en_US
dc.identifier.endpage86en_US
dc.identifier.issn1129-8723
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85016262977en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://hdl.handle.net/11616/91032
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMattioli 1885 S.p.A.en_US
dc.relation.ispartofProgress in Nutritionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterial activityen_US
dc.subjectCallusen_US
dc.subjectScutellaria orientalis subsp. bicoloren_US
dc.titleIn vitro callus propagation and antibacterial activities of callus an edible endemic and medicinal plant Scutellaria orientalis L. Subsp. bicoloren_US
dc.typeArticleen_US

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