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Öğe Affective temperament profile in ankylosing spondylitis patients using TEMPS-A(Society of Physical Therapy Science (Rigaku Ryoho Kagakugakkai), 2017) Yildirim T.; Solmaz D.; Emul M.; Akgol G.; Yalvac D.; Ersoy Y.[Purpose] This study aimed to compare the most common dominant affective temperaments in Ankylosing Spondylitis patients and investigate the relationship between the dominant affective temperaments and pain levels, disease activity, quality of life, current depression, and anxiety level in Ankylosing Spondylitis patients. [Subjects and Methods] Fifty-one patients diagnosed with axial spondiloartropathy and forty-two age- and gender-matched control subjects were included in this study. Disease duration, erythrocyte sedimentation rate, serum C-reactive protein, pain by the Visual Analog Scale, disease activity by the Bath Ankylosing Spondylitis Disease Activity Index, functional status by the Bath Ankylosing Spondylitis Functional Index; psychological status by the Beck Depression Inventory, Beck Anxiety Inventory and overall health assessment by the Ankylosing Spondylitis Quality of Life Scale were assessed in patients. The Turkish version of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego Auto Questionnaire was used to determine the dominant affective temperament. [Results] There was no statistical difference in the distribution of temperament subtypes between patients with Ankylosing Spondylitis and the controls. Depressive, anxious, and cyclothymic temperament scores were higher in patients with high values on the Bath Ankylosing Spondylitis Functional Index and Visual Analog Scale. There was a correlation between anxious subtypes of affective temperament scores and the value of Ankylosing Spondylitis Quality of Life Scale. Correlation analysis also found depressive, cyclothymic, irritable, and anxious temperament and psychiatric symptoms to be significantly related. [Conclusion] Affective temperament may contribute to symptoms of depression and anxiety in patients with Ankylosing Spondylitis and may increase disease activity and may reduce their quality of life. © 2017 The Society of Physical Therapy Science.Öğe Antimicrobial susceptibility and serotype distribution of pneumococci strains isolated from meningitis patients(2006) Firat M.; Ersoy Y.; Eşel D.; Bayraktar M.; Çaylan R.; Durmaz R.Treatment of life threatening pneumococcal infections such as meningitis has recently become problematic due to the emergence of antibiotic resistant strains. Antimicrobial susceptibility data usually derived from the studies that included all clinical pneumococcal isolates. However, resistance patterns of this microorganism isolated from meningitis cases in our country are not exactly known. The aim of this study was to determine the antimicrobial susceptibility and serotypes of Streptococcus pneumoniae strains isolated from meningitis cases. This retrospective study was designed in three university hospitals in Turkey and 72 pneumococci isolated from patients with meningitis were evaluated. In this study disk diffusion test and E-test methods were used to determine the susceptibility of pneumococci to some antibiotics. All S.pneumoniae isolates were serotyped using Quellung reaction. Although resistance for oxacillin was found by disc diffusion method in 11 isolates, only six of them were found to be resistant by E-test. By the latter procedure, no resistance was recorded against ceftriaxone and meropenem, while chloramphenicol resistance was found as 1.4%. In our study, erythromycin, ciprofloxacin and levofloxacin resistance were 2.8%, TMP-SMX resistance was 26.4%, while no vancomycin resistance was detected by disk diffusion. In evaluation of 72 pneumococci, we found 16 different serotypes and four isolates could not be serotyped. The serogroup 23 (n: 19) was the most common one followed by serotype 19 (n: 9) and serotype 14 (n: 7). Of six resistant isolates, three pneumococci were serogroup 23 and the remaining were from three different serotype/ serogroups 11, 14 and 19. As a result penicillin resistance in pneumococci isolated from meningitis was low and there was no resistance to ceftriaxone. It seems that ceftriaxone is an appropriate choice for empirical treatment of meningitis in our patients. These findings also revealed that pneumococcal polysaccharide capsule vaccines in use cover most of the invasive pneumococcal serotypes.Öğe Chronic pain and it's management in spinal cord injured patients(1995) Akman M.N.; Ersoy Y.Although, advances in rehabilitation medicine has led considerable improvements in prevention and treatment of complications following spinal cord injuries, chronic pain constitutes a major problem by effecting patients' social integration and life quality. A close collaboration between disciplines, especially Physiatry and Anaesthesiology is essential for diagnosis and treatment. In this article, the literature on spinal cord injury pain and current therapeutic approaches will be reviewed.Öğe The effect of sodium dichloroisocyanurate dihydrate to prevent the environmental transmission of multidrug-resistant acinetobacter Baumanniiin hospital settings(Parlar Scientific Publications, 2020) Duman Y.; Kuzucu C.; Ersoy Y.; Otlu B.Nosocomial infections are a substantial concern as the major cause of morbidity and mortality of hospitalized patients' in the world. Disinfection of inanimate environment, equipment and hospital setting is important to prevent nosocomial infections. Sodium dichloroisocyanurate dihydrate (NaDCC) can be used for disinfection of environment and medical devices. The aims of this study were to determine the efficacy of NaDCC at various concentrations and times against multi-drug resistant Acinetobacter strains. In the first phase of the study, the bactericidal activity of NaDCC to A. baumannii was investigated by quantitative suspension test. In the second phase, the surface activity of NaDCC was tested by surface disinfection application test. In the third phase, before the cleaning of randomly selected patient's room A. baumannii contamination on the inanimate environment objects and equipment was investigated. After the cleaning of the room the effect of NaDCC was tested. As a result of the quantitative suspension test; NaDCC was inhibited the all A. baumannii and ATCC strains. In the surface disinfection application test, it was determined that at the concentration of 1000 ppm and 500 ppm, the activity of NaDCC; at 5th, 30th and 60th minutes was effective to microorganisms at 5 log level, respectively. But at 100 ppm concentration it was effective to at 5th minutes three, at 30th and 60th minutes seven A. baumannii strains at 5 log levels, while it was effective at log 1 level to other A. baumannii strains and S. aureus, E. coli and P. aeruginosa ATCC. As a result of investigation the A. baumannii contamination in patient's room; before the cleaning, we determined A. baumannii contamination on the inanimate objects of room (such as bed surface, bed edges, control device, nightstand, chair) and on equipment (such as stethoscope, steam appliance, blood pressure device, aspirator heads, ventilator surfaces). After the cleaning it was determined that at 1000 ppm concentration at 5th, 30th and 60thminutes NaDCC was effective to A. baumannii at 5 log levels. However, at 500 ppm concentration at 5th minute it was effective at log 5 level except control device. At 30th and 60th minutes of 500 ppm concentration of NaDCC was effective at log 5 level to A. baumannii. At 100 ppm concentration at 5th, 30th and 60th minutes it was effective to A. baumannii strains at log 1 level on inanimate objects and equipment. In low concentration, NaDCC efficacy was reduced against A. baumannii. The application concentration and time of the disinfectant to clean up the equipment and the environment is very important for preventing nosocomial infections and the spread of A. baumannii. Thus, it is necessary to check and follow up the staff and to create clean and disinfection training programs for educating staff. © by PSPÖğe Enterokokkal Infections in Children: Eight-Year Operating Results(AVES, 2011) Ersoy Y.[No abstract available]Öğe Erratum: Comparison of three different combination therapies in the treatment of human brucellosis (Tropical Doctor (2005) 35 (210-212))(2006) Ersoy Y.; Sonmez E.; Tevfik M.R.; But A.D.[No abstract available]Öğe Investigation of beta-lactamase genes and clonal relationship among the extended-spectrum beta-lactamase producing nosocomial escherichia coli isolates(Ankara Microbiology Society, 2015) Görgeç S.; Kuzucu C.; Otlu B.; Yetkin F.; Ersoy Y.Extended-spectrum beta-lactamase (ESBL) producing microorganisms currently cause a major problem. Among theseCTX-M beta-lactamase producing Escherichia coli has also disseminated worldwide as an important cause of both nosocomial and community-acquired infections. The aims of this study were to determine the prevalence of the beta-lactamase genes, antibiotic susceptibilities and clonal relationships of ESBL-producing nosocomial E.coli isolates. A total of 76 ESBL-producing E.coli strains isolated from urine (n= 26), blood (n= 25) and wound (n= 25) specimens of hospitalized patients identified as nosocomial infection agents according to the CDC criteria between June 2010-]une 2011 were included in the study. Antibiotic susceptibilities of the isolates were detected by Kirby-Bauer disc diffusion method according to CLSI recommendations. ESBL production was tested by double disc diffusion method, and cefotaxime/cefotaxime-clavulanic acid E-test strips (AB Biodisk, Sweden) were used for indeterminate results. Presence of TEM, SHV, CTX-M, OXA-2 group, 0XA-10 group, PER, VEB and CES beta-lactamase genes were investigated by polymerase chain reaction (PCR) using specific primers. Pulsed-field gel elec-trophoresis (PFCE) method was used for the detection of clonal relationships among the strains. Most of the ESBL-producing E.coli strains were isolated from samples of inpatients in intensive care (35%), internal medicine (16%) and general surgery (13%) units. All of the 76 strains were found susceptible to imipenem, meropenem and amikacin; however all were resistant to cefotaxime and ceftriaxone. The susceptibility rates of the isolates to cefoxitin, ertapenem, cefoperazone/sulbactam, piperacillin-tazo- bactam, gentamicin, ciprofloxacin, cefepime, amoxicillin-davulanic acid, aztreonam and ceftazidime were 96%, 83%, 63%, 61%, 50%, 41%, 25%, 21%, 20% and 18%, respectively. Among E.coli isolates, the frequency of CTX-M, TEM, OXA-2 group, PER, SHV and OXA-10 group beta-lactamase genes were found as 89.5%, 59.2%, 15.8%, 14.5%, 11.8% and 3.9%, respectively, while none of the isolates were positive for VEB and CES beta-lactamase genes. In 1 (1.3%) strain none of the investigated genes were detected. PCR analyses of the isolates revealed that 25 harbored CTX-M and TEM genes together, while 20 harbored only CTX-M and two harbored only TEM genes. Single SHV gene was not detected in any of the isolates. PFCE demonstrated no major clonal relationship between ESBL-producing isolates. This study indicated that CTX-M type enzymes were highly endemic among ESBL-producing nosocomial E.coli strains in our hospital, with the polyclonal spread of ESBL-producing bacteria without any dominant epidemic clone. In conclusion, it was considered that further studies are needed to explain the relationship between epidemic clones and plasmids with the use of plasmid analysis and multilocus sequence typing methods.Öğe Investigation of glycopeptide resistance in enterococcal strains isolated from Malatya, Kayseri and Elazi? Medical Faculty Hospitals(2001) Ersoy Y.; Sönmez E.; Young H.J.; A?el E.; Durmaz B.Enterococci are now receiving increased attention because of their resistance to multiple antimicrobial drugs, which probably explain their importance in nosocomial infections. The incidence of glycopeptide resistance of enterococci and detailed information about resistance genes has not yet been well recognized in our country. The aim of this study was to investigate the phenotypic and genotypic resistance of enterococci to glycopeptides, which were isolated from clinical specimens of patients in Medical Faculty Hospitals of Malatya, Kayseri and Elazi? Universities between the period from January 1998 to September 1999. A total of 235 enterococcus strains were included to the study and MIC values of vancomycin and teicoplanin for all isolates were determined by agar dilution method. All isolates were found to be susceptible to teicoplanin, but 11 strains showed intermediate resistance to vancomycin (4?g/ml?MIC?12?g/ml), while others were all susceptible. The vancomycin resistance genes of these 11 strains were investigated by single step polymerase chain reaction. As a result, vanC genes were detected in 7 strains and vanC2-3 genes in 2 strains, while there were no resistance genes in the other 2 isolates. In none of the strains vanB genes were positive. In conclusion, it has been suggested that the incidence of vancomycin resistance of enterococci in our region is not as high as in the other countries.Öğe Investigation of serum IgG subclass distributions and anti-HBs response in healthy adults after hepatitis B vaccination(2005) Dinç But A.; Ersoy Y.; Özerol I.H.; Firat M.The aim of this study was to evaluate the distribution of serum total lgG (tlgG) subtypes before and after hepatitis B vaccinations in young adults and the relationship between anti-HBs titers and tlgG subtypes. Thirty-eight young adults (29 female, 9 male; age range: 18-20 years) who were the students of Malatya Health Care Profession High School were included in the study. Their anti-HBs and total anti-HBc markers' were negative. The study group were immunized with 20 ?g/mL recombinant HBV vaccine intramuscularly (Engerix B) at 0, 1st, and 6th months. The tlgG subtype distributions before vaccination and anti-HBs and tlgG subtype distributions after vaccination were investigated. Serum samples were collected one month after the third dose vaccination, and anti-HBs were found negative (<10 IU/ml) in 8 subjects (21%), low positive (10-100 IU/ml) in 14 subjects (37%), and high positive (>100 lU/ml) in 16 subjects (42%). There was no difference between the response groups in terms of tlgG subtype distributions obtained before vaccination. After vaccination, while there was no increase in the tlgG subtypes in the unresponsive group, increased lgG1 levels were determined in low and high response groups. The lgG1 increment ratio was more evident in high response cases. We concluded that lgG1 subtype titer was the most important indicator for the evaluation of the efficacy of active HBV immunization.Öğe A new orthosis for trapezius palsy following radical neck dissection in patients with head and neck cancer(1995) Akman M.N.; Sari Z.; Ersoy Y.; Saydam L.Serious shoulder malalignment which causes pain and dysfunction as well as cosmetic disturbance, constitutes a major problem following radical neck dissection in patients with head and neck cancer. Complete lesion or enbloc removal of the accessory nerve during surgery results in paralysis of the trapezius muscle, main stabilizer of the scapula. Loss of its function causes ipsilateral shoulder depression and protraction, decreased active range of motion and disabling pain associated with strain and stretch of the rhomboids and levator scapula muscles. We developed a new orthosis, 'Akman-Sari Trapezius Palsy Orthosis', to correct shoulder malalignment and relieve pain in these patients. Here, we describe our orthosis and present a case in whom we have got excellent results with this orthosis.Öğe The value of mammographic magnification technique in the evaluation of hand and wrist radiographs in rheumatoid arthritis(2002) Baysal Ö.; Baysal T.; Alkan A.; Fidan F.; Altay Z.; Ersoy Y.The purpose of this study was to determine the efficacy of direct magnification radiographs in comparison to optically magnified conventional radiographs in the diagnosis of erosive changes and joint space narrowing seen in the hand and wrists of rheumatoid arthritis patients. In thirty one rheumatoid arthritis patients (26 women and 5 men) dominant hand conventional radiographs magnified with a hand lens and direct magnified radiographs (1.5X) using the standart magnification equipment of the mammography unit were compared. A scoring system was used in the evaluation of erosive changes and joint space narrowings. Total scores of both erosions (p<0.0001) and joint space narrowing (p<0.02) were significantly higher in direct magnification radiographs compared to optically magnified conventional radiographs. In early rheumatoid patients, with a disease duration of less than one year, total score of erosions was significantly higher in direct magnification technique compared to optical magnification technique (p<0.001). Our findings revealed that, direct magnification radiographs obtained using standart magnification equipment of the mammographv unit were superior to opticallv magnified conventional radiographs in demonstrating erosive changes particularly in the hands and wrists of patients with early rheumatoid arthritis.
