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Öğe All Concha Bullosa: An Undefined Abnormality of the Lateral Nasal Wall(Springer, 2013) Toplu, Yuksel; Bayindir, Tuba; Karatas, Erkan; Akarcay, MustafaPneumatization of the turbinates, are the anatomic variations of lateral nasal wall. Turbinate pneumatization, refers to the existence of air cell inside the turbinates. Pneumatization of the middle turbinate is common, whereas rare in the superior and especially inferior turbinate. In this report we presented a case who has bilaterally pneumatization of all conchas.Öğe Auricular calcification: Case report of petrified ears in a woman(2021) Ozer Ozturk, Ebru; Karatas, ErkanAuricular calcification (Petrified ears) is one of the rare diagnoses in ENT outpatient clinics. Although auricular calcification is often asymptomatic and does not require treatment, it is a critical diagnosis since it may develop secondary to life-threatening endocrinopathies. A 33-year-old female patient was admitted to our clinic with increasing stiffening in both auricles for one year. On physical examination, bilateral tympanic membranes, external auditory canals, and auriculas had a natural appearance. Apart from lobules, the bilateral auricle had lost its elasticity. Computed tomography of the temporal bones showed bilateral calcification of auriculas and external auditory canals with normal soft-tissue density of the overlying subcutaneous tissues. In our study, a patient who was followed up due to pituitary insufficiency, and she has complained about the progressive loss of elasticity in both auricles was discussed.Öğe The comparison of acoustic and psychic parameters of subjective tinnitus(Springer, 2012) Karatas, Erkan; Deniz, MuratWe aim to assess the correlation between audiometric data, and psychotic and acoustic measures associated with subjective tinnitus (ST) and to clarify the importance of the psychological process in determining the degree of subjective annoyance and disability due to tinnitus. Fifty-four patients experiencing unilateral ST were allocated for the study. Acoustic assessment of patients including LDL (loudness discomfort levels), MML (minimum masking level) and RI (residual inhibition) was performed. Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI) and Visual Analog Scale (VAS) tests were performed for the psychological aspects of subjective annoyance. RI was positive in 23 patients with 13 frequency-matched stimuli at 8,000 Hz. Masking treatment response was successful in 16 RI-positive patients. Mean and standard deviation (SD) of THI scores were 38.77 +/- A 23.63. Ten patients (%18.51) with tinnitus had a parts per thousand yen17 points score, which was significant for BDI. Mean and SD were 5.01 +/- A 2.31 for VAS-1 scores (severity of tinnitus), 7.98 +/- A 2.79 for VAS-2 (frequency and duration of tinnitus), 5.77 +/- A 2.72 for VAS-3 (discomfort level), 3.56 +/- A 3.30 for VAS-4 (attention deficit) and 3.31 +/- A 3.31 for VAS-5 (sleep disorders). A significant correlation was found between the tinnitus duration time, age, gender and THI scores (P < 0.05). There were statistically significant correlations between VAS 1, 2, 3 scores and LDL, MML and RI (P > 0.05). RI might be largely frequency dependent and was found as an indicator for the masking treatment response. We did not notice statistically significant correlations between audiometric data and THI and BDI. There were correlations between with VAS and LDL and with MML and RI. VAS was simpler and easier for the assessment of ST. We should consider the psychological aspects of ST and assess it as a symptom separately with acoustic and psychotic tests.Öğe Comparison of surgical and audiological outcomes of endoscopic and microscopic approach in stapes surgery(Professional Medical Publications, 2019) Gulsen, Secaattin; Karatas, ErkanObjective: The main objectives of the present study were to compare the surgical and audiological outcomes of endoscopic and microscopic approach in stapes surgery. Methods: Sixty-one patients who underwent the stapes surgery with the endoscopic and microscopic approach between January 2012-November 2018 were included in the study. Patients were divided into two groups as a Group-I (endoscopic) and Group-II (microscopic). The audiometric measurements, duration of surgery, intraoperative findings and complications were recorded and evaluated retrospectively. Results: Mean operative time for the Group-I and II was 45.1 +/- 8.4 minutes and 48.7 +/- 5.6 minutes, respectively (p>0.05). The preoperative and postoperative average air-bone gap in the Group-I was 27.8 +/- 7.2 dB and 8.7 +/- 3.4 dB and these values in Group-II were 30.2 +/- 5.1 dB and 7.4 +/- 4.8 dB, respectively (p<0.001). The requirement of chorda tympani nerve manipulation and scutum curettage were significantly less in Group-I as compared Group-II (p<0.05). Dysgeusia and postoperative pain were observed significantly higher ratios in Group-II relative to Group-I (p<0.05). There was no significant difference between endoscopic and microscopic approach in stapes surgery in terms of difficulty of prosthesis insertion (p>0.05). Conclusion: Endoscopic stapes surgery provides comparable audiological outcomes, shorter operative times, fewer complications rates, and more minimally invasive surgery, relative to the microscopic approach.Öğe Congenital Aplasia of the External Ear Canal and Total Dehiscence of Mastoid-Tympanic Segment of the Facial Nerve as a Cause of Recurrent Facial Paralysis(Lippincott Williams & Wilkins, 2013) Toplu, Yuksel; Kalcioglu, Mahmut Tayyar; Karatas, Erkan; Bayindir, TubaFacial nerve (FN) macrodehiscence, in contrast to microdehiscence, generally occurs as a result of chronic otitis media and is rarely seen congenitally. A patient with normal hearing who had no history of ear disease or ear operation came to the clinic with recurrent facial paralysis (FP) and frequent blockage of the external ear canal with epithelial debris complaints. In the explorative ear surgery, we observed that the posterior wall of the external ear canal or tympanic ring was absent, a large external ear cavity was covered with a thin skin, the FN was under the skin, and the tympanic-mastoid segment of the FN and chorda tympani extending to the stylomastoid foramen was completely open. FP episodes were associated with the unprotected FN. To prevent an attack of FP, and to self-clean the external ears, mastoid obliteration surgery was performed, and the mastoid segment of the FN was covered with a conchal cartilage graft. This case was diagnosed as congenital aplasia of the external ear canal due to the tympanic bone aplasia-mastoid bone hypoplasia, and the dehiscence of the mastoid-tympanic segment of the FN, and as a cause of recurrent FP, has never to date been identified.Öğe Does cartilage thickness affect hearing results in real life? Long-term results of cartilage and fascia graft in type 1 tympanoplasty(Wiley, 2019) Kalcioglu, Mahmut Tayyar; Tuysuz, Ozan; Yalcin, Muhammed Zeki; Karatas, Erkan[Abstract Not Available]Öğe Effects of Topical Phenytoin on Nasal Wound Healing After Mechanical Trauma: An Experimental Study(Wiley, 2014) Simsek, Gokce; Ciftci, Osman; Karadag, Nese; Karatas, Erkan; Kizilay, AhmetObjectives/HypothesisImpaired postoperative wound healing is the second most common morbidity after synechia formation in endoscopic sinus surgery. The aim of this experimental study was to investigate the potential effects of topical phenytoin on wound healing after nasal mucosal trauma in rats. Study DesignAn experimental study at the Inonu University Faculty of Medicine. MethodsTwenty-four rats were randomized into three groups: 1) phenytoin group (n=8), 2) control group (n=8), and 3) vehicle group (n=8). After damaging the right nasal cavity, in the phenytoin group, 1% topical phenytoin cream was applied for 7 days. The rats in the control group did not receive any treatment. The vehicle group was treated with daily topical cold cream for 1 week. The rats were sacrificed at the end, and the nasal cavities were excised. Tissue edema and inflammatory cell infiltration were compared among the groups. Additionally, proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) immunoexpression levels were evaluated. Furthermore, in biochemical analysis, the tissue levels of vascular endothelial growth factor and (EGF) of the groups were investigated. ResultsIn the phenytoin group, tissue edema and inflammatory cell infiltration were significantly decreased, and PCNA and CD31 immunoexpression levels were more prominent (P<.001) and the tissue EGF levels were significantly higher (P<.01). ConclusionsTopical phenytoin treatment may alter the nasal wound healing after mechanical trauma. The potential beneficial effects of topical phenytoin on nasal mucosa should be investigated by further experimental and human trials. Level of EvidenceNA Laryngoscope, 124:E449-E454, 2014Öğe Evaluation of the treatment results of laryngeal carcinoma: our experience over 10 years(Tubitak Scientific & Technological Research Council Turkey, 2012) Karatas, Erkan; Baysal, Elif; Durucu, Cengiz; Baglam, Tekin; Bayazit, Yildirim Ahmet; Kanlikama, MuzafferAim: To retrospectively analyze the treatment results for laryngeal carcinoma and to find the impact of the clinical parameters on the survival of the patients. Materials and methods: The medical records of 150 consecutive patients, operated on for laryngeal squamous cell carcinoma between 1991 and 2009, were reviewed. Tumor localization, TNM stages, treatment modalities, radiotherapy, second primary tumors, and tumor recurrence were recorded, and the survival data were obtained. Results: Neck metastasis was rare (3.6%) in T1 and T2 glottic tumors, while there was a significant increase in the rate of N+ neck (35%) in T3 and T4 glottic tumors (P < 0.05). N+ neck was encountered in 28% of the early and 33% of the late-stage supraglottic cancers (P > 0.05). There was a significant relation between survival and tumor recurrence (P < 0.05), whereas the other clinical parameters were not associated with survival (P > 0.05). The risk for death of the disease increased by 63.3% when tumor recurrence occurred (odds ratio = 6.3573). Conclusion: Aggressive treatment of the primary tumor and neck may eliminate the impact of advanced tumor stage on survival. Local and regional recurrence and second primary diagnosis are the most important factors involved in survival in laryngeal carcinoma.Öğe Giant Concha Bullosa Pyocele: An Unusual Cause of Rapidly Developing Nasal Obstruction(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2014) Toplu, Yuksel; Bayındır, Tuba; Gullu, Serdar; Karatas, Erkan; Kızılay, AhmetConcha bullosa pyocele is an uncommon intranasal disorder and appears when concha bullosa becomes infected. In this pathology, middle concha may become expanded and can compress surrounding tissues. If it is not appropriately treated with the necessray surgical method, this pathology may lead to intracranial and orbital complications. In this paper, we would like to report a case of giant concha bullosa pyocele which has lead to nasal obstruction and headache for two months. The resection of the lateral wall of concha bullosa was performed by transnasal endoscopic procedure. No complications were seen during or after the operation. There were no complaints reported by the patient at the follow-up period and the control endoscopic nasal examination was completely normal. The study aims to provide a consciousness of concha bullosa pyocele in the diferential diagnosis of patients with rapidly developing nasal obstruction and headache.Öğe Intra- and postoperative electrically evoked stapedius reflex thresholds in children with cochlear implants(Elsevier Ireland Ltd, 2012) Baysal, Elif; Karatas, Erkan; Deniz, Murat; Baglam, Tekin; Durucu, Cengiz; Karatas, Zeynel Abidin; Mumbuc, SemihObjectives: The aim of this study was to investigate whether there is a significant correlation between intra- and postoperative electrically evoked stapedius reflex thresholds (eSRTs) in children with cochlear implants. Methods: Sixty-five pediatric cochlear implant users were included in this study. All patients had congenital prelingual hearing loss. The round window approach was used in all patients. The eSRTs were intraoperatively measured using the 1st, 3rd, 6th and 12th electrodes of the cochlear implant. The measurements taken during the first fitting of the device were taken again one month after surgery. We used paired-sample t-tests to determine the correlation between intra- and postoperative eSRTs. Results: The eSRT analysis revealed a statistically significant difference between the intra- and postoperative thresholds. A correlation analysis did not reveal any correlation between intra- and postoperative eSRTs. Conclusion: Intraoperative eSRT measurements were unable to predict early postoperative eSRTs. (C) 2012 Elsevier Ireland Ltd. All rights reserved.Öğe Intraoperative electrically evoked stapedius reflex thresholds in children undergone cochlear implantation: Round window and cochleostomy approaches(Elsevier Ireland Ltd, 2011) Karatas, Erkan; Aud, Murat Deniz; Baglam, Tekin; Durucu, Cengiz; Baysal, Elif; Kanlikama, MuzafferObjectives: To study the best electrically stimulation in cochlear implant surgery with round window (RW) and Promontory cochleostomy approaches with electrically evoked stapedius reflex thresholds (ESRT) intraoperatively. Methods: Thirty-nine children underwent CI surgery were included for this study. The surgical procedures consisted of RW and Promontory cochleostomy. ESRT for each 1st, 3rd, 6th and 12th electrodes (E) were determined. Statistical evaluation was done for the comparison of the thresholds and duration times for both groups. Results: The duration times of ESRT for E1, E3, E6 and E12 electrodes was shorter in RW group compared with the Promontory group (p < 0.05). The statistical evaluation of ESRT measurements of E1, E3, E6 found p < 0.001 and E12 electrode p < 0.05 in RW group. ESRT measurements were recorded at lower threshold in the RW group compared with the Promontory group. Conclusion: The duration of electrically stimulation thresholds were shorter in RW group. ESRT measurements were recorded at lower threshold in the RW group compared with the Promontory group. RW insertion offers best electrically stimulation relative to electrode insertion via a promontory cochleostomy. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Öğe Nasolacrimal duct obstruction with obstructive nasal deformity; is synchronous nasal surgery necessary?(2021) Toplu, Yuksel; Bayindir, Tuba; Balbaba, Mehmet; Kalcioglu, Mahmut Tayyar; Sapmaz, Emrah; Karatas, ErkanThe aim of this study was to evaluate the necessity of the simultaneous additional nasal surgery to increase success rate of the endoscopic dacryocystorhinostomy operation, in the patients with nasolacrimal duct obstruction and obstructive nasal deformity. One hundred and thirty patients with nasolacrimal duct obstruction and obstructive nasal deformity (59 were female and 71 male, age ranged between 31 and 82 years, mean=60.3 years) were included in this study. Patients with nasolacrimal duct obstruction were divided into two main groups (group A and B) and six subgroups (A1, A2, A3 and B1, B2, B3) according to the presence of obstructive nasal deformity and applied operation techniques. The success and complications rates of this groups were evaluated. The success rates of endoscopic dacryocystorhinostomy in the additional nasal surgery performed group (Group A) were not statistically significant higher than the group without additional nasal surgery (Group B). Complications rate of group A (26.08%) were statistically significant higher than group B (9.8%). In patients with complications, the average success rate of endoscopic dacryocystorhinostomy surgery (70.8%) was statistically significant lower than in patients with no complications (88.6%), respectively. Additional nasal surgery has no statistically significant effect on the success of the endoscopic dacryocystorhinostomy surgery. Developing complications was statistically affect the success rate of endoscopic dacryocystorhinostomy surgery. Due to these reasons, contrary to the general idea, we believe that, to increase the success rate of the endoscopic dacryocystorhinostomy surgery, additional nasal surgery is unnecessary in patients with nasolacrimal duct obstruction and obstructive nasal deformity.Öğe New Diagnostic and Therapeutic Approaches in Otologic Diseases(Hindawi Publishing Corporation, 2013) Oghan, Fatih; Cingi, Cemal; Karatas, Erkan; Cureoglu, Sebahattin[Abstract Not Available]Öğe Objective Evaluation of the Prosthesis Diameter on Hearing Results after Stapedotomy(Mediterranean Soc Otology & Audiology, 2012) Karatas, Erkan; Deniz, Hale CamObjective: To evaluate objectively the Teflon piston diameters on hearing results in otosclerosis patients undergone stapedotomy. Materials and Methods: The diameters of prostheses used were 0.3 mm and 0.6 mm in two groups of ten patients. and 10 healthy patients as control group were included. Transient evoked otoacoustic emissions (TEOAE), Distortion product otoacoustic emissions (DPOAE) and DPOAE I/O functions were recorded. Results: Significant changes were detected at 2000-3000 Hz (p<0.001) and 4000-6000 Hz (p<0.05) for 0.6 mm prostheses in TEOAE statistically. Also 3000-4000 Hz for 0.6 mm prostheses (p<0.05) for DPOAE and with 65 dB at 2000 Hz (p<0.05), with 60 dB and 45 dB at 3000 Hz (p<0.05) for DPOAE I/O were found statictically. Conclusions: OAE measurements are advisable for follow-up examinations in otosclerosis patients with stapedotomy. An increase in prosthesis diameter for stapedotomy gives better hearing results, not only at lower frequencies, but also at higher.Öğe Outcomes of cochlear implantation in children with and without inner ear malformations(Professıonal medıcal publıcatıons, panorama centre, rm 522, 5th floor, bldg 2, raja ghazanfar alı rd, po box 8766, saddar, karachı 00000, pakıstan, 2018) Celik, Mustafa; Karatas, Erkan; Kanlikama, MuzafferObjective: To evaluate the auditory functions and progress of speech development in children with and without cochlear anomalies who underwent cochlear implantation due to prelingual profound sensorineural hearing loss (SNHL). Methods: This study was conducted at Gaziantep University Faculty of Medicine Ear-Nose-Throat Department, between October 2006 and December 2007. A total of 69 children (aged 6 to 24 months) diagnosed with profound SNHL were included. Patients were divided into two groups with respect to the presence of inner ear anomalies: Group-1 consisted of 41 children without inner ear anomaly, whereas Group-2 was composed of 28 patients with inner ear anomalies. The auditory performance was assessed using Listening Progress Profile Test (LPPT) and Monosyllabic Trochee Polysyllabic Test (MTP), the subsections of Evaluation of Auditory Responses to Speech (EARS) test battery. Results: Preoperative LPPT scores were 5 (12%) in both groups. Mean LPPT values after fitting in Group-1 and Group-2 on 1st, 3rd and 6th months were 18.5 (44.1%) and 19 (45.6%); 27 (64.2%) and 28 (67.3%); 31 (75%) and 34 (83%), respectively. Postoperatively, MTP scores in Group-1 and Group-2 were 7.5 (62%) and 7.7 (64%) for 3-words set; 10.4 (58%) and 10.6 (59%) for 6-words set; 14.3 (60%) and 14 (59%) for 12-words set, respectively. The rate of stimulation for electrodes was 1345 q/u (quick/unit) in Group-1 and 1310 q/u in Group-2. No statistically significant difference was detected between groups for variables under investigation. Conclusion: Cochlear implantation is an effective treatment in children with prelingual profound SNHL. Auditory performance and advancement of speech are similar for children with and without inner ear anomalies.Öğe Outcomes of cochlear implantation in children with and without inner ear malformations(Professional Medical Publications, 2018) Celik, Mustafa; Karatas, Erkan; Kanlikama, MuzafferObjective: To evaluate the auditory functions and progress of speech development in children with and without cochlear anomalies who underwent cochlear implantation due to prelingual profound sensorineural hearing loss (SNHL). Methods: This study was conducted at Gaziantep University Faculty of Medicine Ear-Nose-Throat Department, between October 2006 and December 2007. A total of 69 children (aged 6 to 24 months) diagnosed with profound SNHL were included. Patients were divided into two groups with respect to the presence of inner ear anomalies: Group-1 consisted of 41 children without inner ear anomaly, whereas Group-2 was composed of 28 patients with inner ear anomalies. The auditory performance was assessed using Listening Progress Profile Test (LPPT) and Monosyllabic Trochee Polysyllabic Test (MTP), the subsections of Evaluation of Auditory Responses to Speech (EARS) test battery. Results: Preoperative LPPT scores were 5 (12%) in both groups. Mean LPPT values after fitting in Group-1 and Group-2 on 1st, 3rd and 6th months were 18.5 (44.1%) and 19 (45.6%); 27 (64.2%) and 28 (67.3%); 31 (75%) and 34 (83%), respectively. Postoperatively, MTP scores in Group-1 and Group-2 were 7.5 (62%) and 7.7 (64%) for 3-words set; 10.4 (58%) and 10.6 (59%) for 6-words set; 14.3 (60%) and 14 (59%) for 12-words set, respectively. The rate of stimulation for electrodes was 1345 q/u (quick/unit) in Group-1 and 1310 q/u in Group-2. No statistically significant difference was detected between groups for variables under investigation. Conclusion: Cochlear implantation is an effective treatment in children with prelingual profound SNHL. Auditory performance and advancement of speech are similar for children with and without inner ear anomalies.Öğe Persistent Facial Paralysis to Delayed Diagnosis of Ramsay Hunt Syndrome(Galenos Publ House, 2011) Karatas, Erkan[Abstract Not Available]Öğe Protective effects of resveratrol on salivary gland damage induced by total body irradiation in rats(Wiley-Blackwell, 2012) Simsek, Gokce; Gurocak, Simay; Karadag, Nese; Karabulut, Aysun Bay; Demirtas, Erol; Karatas, Erkan; Pepele, EdaObjectives/Hypothesis: One of the most common acute side effects of irradiation is xerostomia, which results from damage to the salivary gland cells by direct ionization. Resveratrol is a natural compound with profound anti-inflammatory and antioxidant properties. The purpose of the present study was to investigate the potential protective effects of resveratrol on injury to the salivary glands of rats that were exposed to total body irradiation. Study Design: An experimental study at the Inonu University School of Medicine. Methods: Twenty-nine female rats were randomized into four groups: group 1, high-dose (100 mg/kg) resveratrol group (n = 7); group 2, low-dose (10 mg/kg) resveratrol group (n = 7); group 3, control (vehicle) rats (n = 7); and group 4, sham-irradiation group (n = 8). The medications were administered as single doses, and the rats were exposed to total body irradiation 24 hours after the treatment. The animals were sacrificed the following day, and the parotid and submandibular glands were excised. Salivary gland histology and the tissue levels of glutathione (GSH), nitric oxide (NO), and malondialdehyde (MDA) were investigated. Results: The rats in group 1 showed significantly decreased acinar loss and less ductal damage and cell necrosis than those of the control group (P < .05). Antioxidant GSH levels were significantly increased by high doses of resveratrol treatment. The tissue activities of MDA in both the parotid and submandibular glands were significantly reduced in group 1. Low-dose resveratrol treatment did not significantly alter the tissue levels of MDA. Conclusions: Resveratrol at relatively high doses can reduce the irradiation-dependent salivary gland damage, suggesting that this natural antioxidant may be effectively used to lessen the side effects related to salivary gland dysfunction that is induced by irradiation. Laryngoscope, 2012Öğe The Protective Role of Molsidomine on the Cisplatin-Induced Ototoxicity(Springer India, 2014) Toplu, Yuksel; Parlakpinar, Hakan; Sapmaz, Emrah; Karatas, Erkan; Polat, Alaattin; Kizilay, AhmetThis experimental study was designed to investigate the protective effects of molsidomine (MOL) on against cisplatin-induced ototoxicity (CIO). To examine this effect, distortion product otoacoustic emissions (DPOAEs) measurements and serum levels of oxidative and antioxidant status [including malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPX), total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI)] were evaluated. Thirty-two female wistar albino rats were divided into four groups including; control (Group K), cisplatin (Group C), cisplatin plus MOL group (Group CM), and MOL group (Group M). DPOAEs measurements between 0.9961 and 8.0003 Hz as DP-gram and input/output (I/O) functions were performed in the same (left) ear of all rats on days 0, 1st, 5th and 12th. Prior to death, the last DPOAEs measurements and blood samples were taken. In the C group, statistically significant DPOAE amplitude reductions were detected at 2.5195, 3.1758, 3.9961, 5.0391, 6.3516 and 8.0039 Hz frequencies (p < 0.05) between 0th and 1st, 0th and 5th and 0th and 12th days' measurements (p < 0.05). Serum level of MDA, TAC and OSI levels were significantly higher in the C group versus K group (p < 0.05). In the CM group, there were no significant differences at all frequencies between 0th and other days' measurements (p[0.05) and the serum levels of all biochemical parameters were shifted toward normal values, similar to the K group (p < 0.05). No significant differences were detected in the either M or K group's measurements. According to these results, cis-platin-related ototoxicity has been significantly prevented by MOL.Öğe Repair of Cerebrospinal Fluid Leak in Cochlear Implantation(Lippincott Williams & Wilkins, 2019) Karatas, ErkanObjective: The aim of this study is to evaluate the treatment of cerebrospinal fluid (CSF) leaks from cochleostomy after cochlear implantation intraoperatively and postoperatively. Methods: Three hundred seven patients (age ranges 13 months to 18 years) were undergone cochlear implantation and 14 (4.56%) of them had CSF leakage intraoperatively (2 normal, 12 anomalous cochlea). Complete packing of the around electrode in cochleostomy with muscle had performed to control CSF leak intraoperatively for primary surgery in 10 patients. Cerebrospinal fluid leakage was observed in 3 patients after cochlear implantation postoperatively. Revision surgeries for CSF leakage with fat tissue sealing were performed for them also. Fat tissue packing was performed for the last 4 patients in primary surgery. Outcomes of management methods for sealing were evaluated. Results: Sealing the cochleostomy with muscle was performed for 10 patients. Fibrin glue applications were used for excessive leakage for 5 patients with cochlear anomalies and 3 of these patients had CSF leak from cochleostomy postoperatively (Patients I, II, III). Secondary surgeries with fat tissue sealing were performed. But CSF leakage also was occurred in Patient III. Subtotal petrosectomy and obliteration of cavity with fat tissue had been performed for Patient III. Cerebrospinal fluid leakage has not been seen in primary surgeries with fat tissue packing in other 5 patients. Conclusion: Cerebrospinal fluid leakage may occur in cochlear implantation patients with inner ear anomalies postoperatively. Sealing of the cochleostomy with fat tissue is more useful than muscle intraoperatively.
