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Öğe Endoscopic retrograd cholongiopancreatography results in diagnosis and therapy(1999) Hilmioglu F.; Yildirim B.; Karincaoglu M.; Aladag M.; Taskin V.; Kantarceken B.The use of diagnostic and therapeutic endoscopy for pancreaticobiliary disease has increased in recent years. Choledocholithiasis and malignant strictures are most common diagnosis on endoscopic retrograde cholangiopancreatography (ERCP). We reviewed our recent experience to assess the spectrum of procedures performed and their results. Medical records and radiographic examinations of 338 consecutive patients undergoing therapeutic ERCP were studied. The most common diagnoses were choledocholithiasis and malignant strictures. Successful cannulation was 91.7% and successful treatment was 90%.Öğe Endoscopic treatment of biliary fistulas: Results of 20 patients(1999) Hilmioglu F.; Yildirim B.; Karincaoglu M.; Aladag M.; Kantarceken B.; Dogan I.Biliary fistula is an infrequent but serious complication which usually occurs following biliary tract surgery. In this study treatment consisted of standard sphincterotomy and if necessary, stone extraction with or without endoprosthesis placement. The aim of all treatments was to facilitate bile flow into the duodenum. The biliary tract and site of leakage were visualized during endoscopic retrograde cholangiopancreatography (ERCP) in all patients (100%) and 16 of 20 patients were treated endoscopically (80%). Bile leakage can be diagnosed safely and effectively by ERCP and subsequent endoscopic management is successful in most cases.Öğe Evaluation of choledochal stones(1999) Karincaoglu M.; Aladag M.; Yildirim B.; Hilmioglu F.We present a four year review of patients with suspected gallstones, in whom endoscopic retrogade cholangiopancreatography (ERCP) was performed prior to cholecystectomy. ERCP was performed on 84 patients with a provisional diagnosis of gallstones but stones were found in only 53 of these patients. The most sensitive diagnostic screening method was found to be alkaline phosphatase while the most specific was screening of intrahepatic bile duct dilation with ultrasound.Öğe Evaluation of protective effects of verapamil against lens epithelial tissue injury induced by irradiation in rats(Turkish Pharmacists Association, 2010) Batçio?lu K.; Erkal H.S.; SerIn M.; Uyumlu A.B.; Yücel N.; Yildirim B.; Satilmiş B.In this study, we investigated the possible protectant effects of verapamil against lens epithelial tissue injury induced by irradiation in rats. Forty female Wistar Albino rats were divided into four groups (n=10). Group 1 received 10 mg/kg verapamil and underwent 20 Gy irradiation. Group 2 received no verapamil and underwent 20 Gy irradiation. Group 3 received 10 mg/kg verapamil and underwent sham irradiation. Group 4 received no verapamil and underwent sham irradiation. The lens tissues were dissected and measured malondialdehyde levels in all groups. The mean malondialdehyde levels (nmol/mg prt) were determined as 5,59 for Group 1, 7,04 for Group 2, 3,95 for Group 3 and 3,25 for Group 4. In conclusion, we can suggest that verapamil as a protectant agent against radiation induced lens epithelial tissue injury.Öğe Gluten-free Diet Improves Iron-deficiency Anaemia in Patients with Coeliac Disease(2000) Sari R.; Yildirim B.; Sevinc A.; Buyukberber S.Two cases of newly-diagnosed asymptomatic coeliac disease with 3 years of unexplained severe iron-deficiency anaemia are presented. Oral iron supplementation had no effect on their serum iron levels and, therefore, had no influence on their anaemia. Upper gastrointestinal endoscopy confirmed normal macroscopic findings. Duodenal biopsies revealed subtotal villous atrophy of the mucosa of the small intestine. A strict gluten-free diet led to an increase in serum iron, resolution of anaemia, and restitution of normal mucosal morphology. Thus, severe iron-deficiency anaemia associated with asymptomatic coeliac disease is responsible to gluten-free diet.Öğe Idiopathic hypoparathyroidism and celiac disease in two patients with previous history of cataract.(2000) Sari R.; Yildirim B.; Sevinc A.; Buyukberber S.We report two patients with idiopathic hypoparathyroidism and celiac disease. Both had undergone surgery for cataract previously. The patients presented with tetany in the absence of gastrointestinal complaints. Investigations showed severe hypocalcemia, hypoparathyroidism, flattening of duodenal villi histologically, and diffuse cerebral and basal ganglia calcifications on CT scan. After a gluten-free diet with calcium supplementation, the clinical situation and biochemical values improved.Öğe The prevalence of lymphoid follicles and intestinal metaplasia in Helicobacter pylori associated clinically significant gastroduodenal diseases(Turkish Society of Gastroenterology, 1999) Taskin V.; Gurer I.; Sari R.; Aydin A.; Yildirim B.; Aladag M.; Hilmioglu F.This study was designed to investigate the prevalence of lymphoid follicle formation and intestinal metaplasia in patients with Helicobacter pylori (H.pylori) associated clinically significant diseases. Biopsies from the antrum, corpus and fundus of stomach were obtained from 153 patients (non-ulcer dyspepsia, n:110; duodenal ulcer n:23, duodenal ulcer complicated by obstruction, n:20) with histopathologically proven H. pylori infection. All biopsies were examined for lymphoid follicle with germinal center and intestinal metaplasia. Lymphoid follicles were found in 44.5% of non-ulcer disypeptic patients, 70% of duodenal ulcer complicated by obstruction patients and in 47.8% of uncomplicated duodenal ulcer patients. In contrast, 15.5% of non-ulcer disypeptic patients and 20% of complicated duodenal ulcer patients had associated intestinal metaplasia while no intestinal metaplasia was observed in uncomplicated duodenal ulcer patients. Intestinal metaplasia incidence was not statistically different among the different gastroduodenal pathologies (P>0.05). However the incidence of lymphoid follicles was significantly higher in patients with complicated duodenal ulcer (P<0.05). Our results indicate that H.pylori infection in complicated duodenal ulcers are relatively chronic and aggressive compared to H.pylori infection in other gastroduodenal disorders.
