Relationship between epicardial adipose tissue and body muscle-to-fat ratio in patients with type 2 diabetes mellitus
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Dosyalar
Tarih
2020
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Abstract: Type 2 Diabetes mellitus (T2DM) is shown as an important risk factor for the development of cardiovascular diseases worldwide. Epicardial adipose tissue (EAT) has been associated with cardiovascular diseases. The body muscle-to-fat ratio measured by bioelectric impedance (BIA) is associated with cardiac dysfunction. In this study, we aimed to evaluate the relationship between EAT and body muscle-to-fat ratio in T2DM patients. The 125 consecutive T2DM patients and 46 healty volunteers included in the study. EAT was measured by using transthorasic echocardiograph (TTE). Data were obtained BIA analysis in all patient. The muscle-to-fat ratio measured by BIA and EAT was compared between the two groups. There was a significant difference between the groups in terms of waist circumference (WC), fat mass, fat mass ratio, muscle mass and muscle-to-fat ratio. E (p<0.001), Em wave (p<0.001), E/A ratio (p<0.001) and E/Em ratio (p=0.014) were significantly lower in the DM group compared to controls. Also, EAT thickness was higher in the DM group (5.78 ± 0.7 vs 4.89 ± 0.7 p <0.001). While a positive correlation was observed between EAT and BMI (r = 0.445, p <0.001), WC (r = 0.401, p < 0.001), Age (r = 0.237, p = 0.008) and disease duration (r = 0.199, p = 0.049), EAT and muscle-to-fat ratio were negatively correlated (r = -0.615, p <0.001). Age and muscle-to-fat ratio were found to be independent predictors for EAT (?= 0.037; p<0.001; ?=-1.403, p<0.001 respectively). The muscleto- fat ratio measured by bioelectrical impedance technique in type 2 DM patients may provide a more accurate estimate for EAT, which has been shown to be associated with cardiovascular events.
Açıklama
Anahtar Kelimeler
Kaynak
Medicine Science
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
2
Künye
HİDAYET S,HİDAYET E (2020). Relationship between epicardial adipose tissue and body muscle-to-fat ratio in patients with type 2 diabetes mellitus. Medicine Science, 9(2), 454 - 458. Doi: 10.5455/medscience.2019.08.9217
