The effects of levobupivacaine versus levobupivacaine plus magnesium infiltration on postoperative analgesia in pediatric tonsillectomy patients

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Küçük Resim

Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

International Journal of Pediatric Otorhinolaryngology

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background: The aim of this study was to evaluate whether the addition of magnesium to levobupivacaine will decrease the postoperative analgesic requirement or not, and to investigate the possible preventive effects on laryngospasm. Methods: Seventy-five children undergoing elective tonsillectomy and/or adenoidectomy surgery. The drug was prepared as only NaCl 0.9% for the first group (Group S, n = 25), levobupivacaine 0.25% for the second group (Group L, n = 25), and levobupivacaine 0.25% plus magnesium sulphate 2 mg/kg for the third group (Group M, n = 25). Pain was recorded at 15th minute, 1st, 4th, 8th, 16th, and 24th hour postoperatively. Pain was evaluated using a modified Children’s Hospital of Eastern Ontario pain scale (mCHEOPS). Incidence of postoperative nausea and vomiting (PONV) was assessed at various time intervals (0—2, 2—6, 6—24 h) by numeric rank score. Patients were followed for laryngospasm for 1 h in recovery room after extubation. Other complications appeared within 24 h postoperatively were recorded. Results: All postoperative CHEOPS values were lower than control in both groups. Analgesic requirement was decreased significantly in both groups in comparison with control patients, but this requirement was significantly lower in Group M ( p < 0.05). Although laryngospasm was not observed in Group M, the difference between groups was not statistically significant. PONV was similar in both groups.

Açıklama

Anahtar Kelimeler

Post-tonsillectomy pain, Levobupivacaine, Magnesium, Laryngospasm, PONV

Kaynak

International Journal of Pediatric Otorhinolaryngology

WoS Q Değeri

Scopus Q Değeri

Cilt

72

Sayı

Künye

Karaaslan, K. Yılmaz, F. Gülcü, N. Sarpkaya, A. Çolak, C. Koçoğlu, H. (2008). The effects of levobupivacaine versus levobupivacaine plus magnesium infiltration on postoperative analgesia in pediatric tonsillectomy patients. International Journal of Pediatric Otorhinolaryngology. 72, 675—681.