Assessment of mucosal changes associated with nasal splint in a rabbit model
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation. Objectives: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model. Methods: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored. Results: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D. Conclusions: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.
Açıklama
Anahtar Kelimeler
Nasal mucosa, Nasal septal perforation, Nasal septum, Tampons surgical
Kaynak
Brazilian Journal of Otorhinolaryngology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
81
Sayı
2
