Assessment of mucosal changes associated with nasal splint in a rabbit model

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dc.authoridBayindir, Tuba/0000-0003-4150-5016
dc.authoridsahin, nurhan/0000-0001-9487-1154
dc.authoridTAN, MEHMET/0000-0001-8557-0886
dc.authoridTurkmen, Samdanci, Emine/0000-0002-0034-5186
dc.authorwosidBayindir, Tuba/ABG-9517-2020
dc.authorwosidsahin, nurhan/ABF-8007-2020
dc.authorwosidTAN, MEHMET/ABI-7574-2020
dc.authorwosidKalcioglu, M. Tayyar/JAC-1515-2023
dc.authorwosidKALCIOGLU, Mahmut Tayyar/I-5884-2013
dc.authorwosidTurkmen, Samdanci, Emine/ABH-4716-2020
dc.contributor.authorTan, Mehmet
dc.contributor.authorKalcioglu, M. Tayyar
dc.contributor.authorSahin, Nurhan
dc.contributor.authorBayindir, Tuba
dc.contributor.authorSamdanci, Emine
dc.contributor.authorFiliz, Aliye
dc.date.accessioned2024-08-04T20:41:17Z
dc.date.available2024-08-04T20:41:17Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation. Objectives: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model. Methods: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored. Results: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D. Conclusions: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.en_US
dc.identifier.doi10.1016/j.bjorl.2014.08.004
dc.identifier.endpage189en_US
dc.identifier.issn1808-8694
dc.identifier.issn1808-8686
dc.identifier.issue2en_US
dc.identifier.pmid25382424en_US
dc.identifier.scopus2-s2.0-84946165280en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage184en_US
dc.identifier.urihttps://doi.org/10.1016/j.bjorl.2014.08.004
dc.identifier.urihttps://hdl.handle.net/11616/97037
dc.identifier.volume81en_US
dc.identifier.wosWOS:000352023600011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isopten_US
dc.publisherAssoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacialen_US
dc.relation.ispartofBrazilian Journal of Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNasal mucosaen_US
dc.subjectNasal septal perforationen_US
dc.subjectNasal septumen_US
dc.subjectTampons surgicalen_US
dc.titleAssessment of mucosal changes associated with nasal splint in a rabbit modelen_US
dc.typeArticleen_US

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