Adenosine deaminase, xanthine oxidase, superoxide dismutase, glutathione peroxidase activities and malondialdehyde levels in the sera of patients with head and neck carcinoma.

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dc.authorscopusid6602540278
dc.authorscopusid6603956791
dc.authorscopusid7102711821
dc.authorscopusid6603551686
dc.authorscopusid6603836580
dc.authorscopusid7003373872
dc.authorscopusid7006625363
dc.contributor.authorKalcioglu M.T.
dc.contributor.authorKizilay A.
dc.contributor.authorYilmaz H.R.
dc.contributor.authorUz E.
dc.contributor.authorGüleç M.
dc.contributor.authorOzturan O.
dc.contributor.authorAkyol O.
dc.date.accessioned2024-08-04T20:01:08Z
dc.date.available2024-08-04T20:01:08Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVES: Clinical and epidemiological findings have provided evidence supporting a role of free radicals in the etiology of cancer. Scavengers and inhibitors of free radical processes have been demonstrated to prevent or delay the neoplastic process. PATIENTS AND METHODS: Adenosine deaminase, xanthine oxidase, superoxide dismutase, and glutathione peroxidase activities and malondialdehyde levels were measured in the sera of 35 patients with head and neck cancers and were compared to those of healthy control subjects. RESULTS: Serum adenosine deaminase activity was found to be significantly increased in the patient group (p<0.001). Compared to the control group, glutathione peroxidase and xanthine oxidase activities and malondialdehyde levels were slightly higher and serum superoxide dismutase activity was slightly lower in the patient group, with none reaching statistical significance. CONCLUSION: The results indicate that serum adenosine deaminase activity may be helpful in the diagnosis and follow-up of head and neck cancers. Further studies with a larger cohort of patients are needed to clarify the exact mechanism of adenosine deaminase elevation.en_US
dc.identifier.endpage22en_US
dc.identifier.issn1300-7475
dc.identifier.issue1-2en_US
dc.identifier.pmid16010092en_US
dc.identifier.scopus2-s2.0-23844546770en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage16en_US
dc.identifier.urihttps://hdl.handle.net/11616/91283
dc.identifier.volume12en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofKulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throaten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadenosine deaminaseen_US
dc.subjectglutathione peroxidaseen_US
dc.subjectmalonaldehydeen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjecttumor markeren_US
dc.subjectxanthine oxidaseen_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectblooden_US
dc.subjectcase control studyen_US
dc.subjectfemaleen_US
dc.subjecthead and neck tumoren_US
dc.subjecthumanen_US
dc.subjectmaleen_US
dc.subjectmiddle ageden_US
dc.subjectprediction and forecastingen_US
dc.subjectsquamous cell carcinomaen_US
dc.subjectAdenosine Deaminaseen_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectAged, 80 and overen_US
dc.subjectCarcinoma, Squamous Cellen_US
dc.subjectCase-Control Studiesen_US
dc.subjectFemaleen_US
dc.subjectGlutathione Peroxidaseen_US
dc.subjectHead and Neck Neoplasmsen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectMalondialdehydeen_US
dc.subjectMiddle Ageden_US
dc.subjectPredictive Value of Testsen_US
dc.subjectSuperoxide Dismutaseen_US
dc.subjectTumor Markers, Biologicalen_US
dc.subjectXanthine Oxidaseen_US
dc.titleAdenosine deaminase, xanthine oxidase, superoxide dismutase, glutathione peroxidase activities and malondialdehyde levels in the sera of patients with head and neck carcinoma.en_US
dc.typeArticleen_US

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