Hepatitis B virus DNA levels according to the Child-Pugh stage in patients with cirrhosis

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dc.contributor.authorDeğirmencioğlu, Arife Zühal
dc.contributor.authorSeçkin, Yüksel
dc.date.accessioned2024-08-04T19:42:32Z
dc.date.available2024-08-04T19:42:32Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and Aims: To compare hepatitis B virus DNA levels accordingto Child-Pugh stage in patients who developed cirrhosis due tohepatitis B virus. Materials and Methods: This study was conductedas retrospectively. Patients who were newly diagnosed with cirrhosisdue to hepatitis B virus infection were included. hepatitis B virus DNA,albumin, bilirubin, and international normalization rate levels werecompared according to the Child-Pugh Scores. Results: A total of 90patients (60 males, 30 females) with a mean age of 52.22±9.42 yearswere included in this study. Each group consisted of 30 patients. HepatitisB virus DNA level was significantly lower in the Group A comparedwith the Group B and C (p=0.031). A significant difference was observedbetween the groups in terms of Child-Pugh scores, albumin, bilirubin,and international normalization rate levels (all p=0.0001). Albuminlevels were lower and international normalization rate levels werehigher in the Group B and C (all p<0.05). Ascites and encephalopathywere detected in 42 (%46,7) and 79 (87,8) patients, respectively. Bothascites and encephalopathy were more common in the Group C. Conclusion:Hepatitis B virus DNA level was significantly lower and albuminand bilirubin levels were relatively normal in the early stages of cirrhosisdue to hepatitis B virus infection. By contrast, ascites and encephalopathywere more common, bilirubin and international normalization ratelevels were elevated, and albumin levels were lower in the later stages(Child-Pugh B and C) of chronic hepatitis B.en_US
dc.identifier.doi10.17941/agd.460769
dc.identifier.endpage73en_US
dc.identifier.issn1303-6629
dc.identifier.issn2149-0600
dc.identifier.issue2en_US
dc.identifier.startpage70en_US
dc.identifier.trdizinid298726en_US
dc.identifier.urihttps://doi.org/10.17941/agd.460769
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/298726
dc.identifier.urihttps://hdl.handle.net/11616/88440
dc.identifier.volume17en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAkademik Gastroenteroloji Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleHepatitis B virus DNA levels according to the Child-Pugh stage in patients with cirrhosisen_US
dc.typeArticleen_US

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