Ischemia modified albumin levels and its association with clinical follow-up in acute renal failure

Basit Öğe Kaydı
dc.contributor.authorUzun, Mehmet
dc.contributor.authorTopaloğlu, Ömercan
dc.contributor.authorKurtulmuş, Yusuf
dc.contributor.authorTurkon, Hakan
dc.contributor.authorDuman, Can
dc.contributor.authorKarakas, Burak
dc.contributor.authorAkar, Harun
dc.date.accessioned2024-08-04T19:51:55Z
dc.date.available2024-08-04T19:51:55Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: In cases with acute ischemia, albumin’s binding capacity for transition metals decreases and the resulting albumin is defined as ischemia modified albumin (IMA). In this study, we aimed to investigate the relationship between IMA and clinical follow-up in patients with acute renal failure (ARF).Material and Methods: Levels of IMA were measured in 51(23 male, 28 female) patients with ARF. Venous blood samples were drawn from patients for biochemical tests and put in plain tubes containing the gel.Results: Mean age of male and female patients was 65.39±15.28 and 70.11±15.25, respectively. The IMA levels in 25.5% of the patients were within the normal range (<400 ABSU), while the IMA levels were higher (>400 ABSU) in 75.5% of the patients. The survival rates of patients in IMA <400 ABSU group for 12 and 24 months were 66.7% and for 30 and 32 months it was 33.3%; while the survival rates of patients in IMA ?400 ABSU group for 12 months were 85.8%, for 24 months were 61.3%, and for 30 and 32 months were 30.6%. No significant difference was determined among survival rates of IMA groups (p=0.719).Conclusion: The comparison between the groups having normal or higher IMA values did not show any significant differences in terms of survival. However, in our study the proportion of patients who needed dialysis during treatment were significantly higher in higher IMA group(IMA?400 ABSU). Therefore, we believe that higher IMA levels may indicate a necessity for dialysis in patients with ARF.en_US
dc.identifier.doi10.5455/jtomc.2016.12.135
dc.identifier.endpage315en_US
dc.identifier.issn1300-1744
dc.identifier.issue3en_US
dc.identifier.startpage310en_US
dc.identifier.trdizinid285152en_US
dc.identifier.urihttps://doi.org/10.5455/jtomc.2016.12.135
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/285152
dc.identifier.urihttps://hdl.handle.net/11616/89366
dc.identifier.volume24en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofİnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleIschemia modified albumin levels and its association with clinical follow-up in acute renal failureen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Turgut Özal Tıp Merkezi Dergisi Koleksiyonu