Synthesis of benzotriazole-amino acid-benzenesulfonamide conjugates and phenylsulfonyl-dipeptides
Küçük Resim Yok
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Arkat Usa Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
L-Amino acids were converted into sulfonamides by reaction with phenylsulfonyl chloride in a basic medium. Subsequent treatment of these sulfonamides with 1H-benzotriazole (BtH) and thionyl chloride at room temp erature yielded benzotriazole-amino acid-benzenesulfonamide conjugates with yields ranging from 42% to 68%. Furthermore, the reaction of the benzotriazole derivatives with free glycine and free phenylalanine resulted in the formation of (phenylsulfonyl)dipeptides.
Açıklama
Anahtar Kelimeler
Benzensulfonamide, benzotriazole, L-amino acids, synthesis
Kaynak
Arkivoc
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
