Synthesis of benzotriazole-amino acid-benzenesulfonamide conjugates and phenylsulfonyl-dipeptides
| dc.contributor.author | Ezugwu, James Anayochukwu | |
| dc.contributor.author | Kucukbay, Hasan | |
| dc.date.accessioned | 2026-04-04T13:31:23Z | |
| dc.date.available | 2026-04-04T13:31:23Z | |
| dc.date.issued | 2024 | |
| dc.department | İnönü Üniversitesi | |
| dc.description.abstract | L-Amino acids were converted into sulfonamides by reaction with phenylsulfonyl chloride in a basic medium. Subsequent treatment of these sulfonamides with 1H-benzotriazole (BtH) and thionyl chloride at room temp erature yielded benzotriazole-amino acid-benzenesulfonamide conjugates with yields ranging from 42% to 68%. Furthermore, the reaction of the benzotriazole derivatives with free glycine and free phenylalanine resulted in the formation of (phenylsulfonyl)dipeptides. | |
| dc.description.sponsorship | TUBITAK (The Scientific and Technological Research Council of Turkey) [E-21514107-115.02-612434/2221]; Idot;nonu University, Turkey [FBG-2024-3240] | |
| dc.description.sponsorship | TUBITAK (The Scientific and Technological Research Council of Turkey) Project No: E-21514107-115.02-612434/2221 Program 2024/1 and & Idot;nonu University, Turkey (BAPB- Grand No-FBG-2024-3240) was acknowledged by the authors for funding this research work at Inonu University Malatya, Turkey. | |
| dc.identifier.doi | 10.24820/ark.5550190.p012.429 | |
| dc.identifier.issn | 1551-7004 | |
| dc.identifier.issn | 1551-7012 | |
| dc.identifier.scopus | 2-s2.0-105030822101 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.uri | https://doi.org/10.24820/ark.5550190.p012.429 | |
| dc.identifier.uri | https://hdl.handle.net/11616/108774 | |
| dc.identifier.wos | WOS:001667189800001 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | Arkat Usa Inc | |
| dc.relation.ispartof | Arkivoc | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.snmz | KA_WOS_20250329 | |
| dc.subject | Benzensulfonamide | |
| dc.subject | benzotriazole | |
| dc.subject | L-amino acids | |
| dc.subject | synthesis | |
| dc.title | Synthesis of benzotriazole-amino acid-benzenesulfonamide conjugates and phenylsulfonyl-dipeptides | |
| dc.type | Article |











