The effects of sebum configuration on Demodex spp. density

Basit Öğe Kaydı
dc.contributor.authorDemirdag, Hatice Gamze
dc.contributor.authorOzcan, Hamdi
dc.contributor.authorGursoy, Sule
dc.contributor.authorBeker Akbulut, Gulcin
dc.date.accessioned2019-10-03T12:59:03Z
dc.date.available2019-10-03T12:59:03Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/aim: Demodex spp. are ectoparasites living in the pilosebaceous units, which feed on the host's sebum and cellular proteins. The protective barrier of the skin consists of sebum secretion, moisture, and the acid mantle. In this study, we aimed to determine the effects of skin sebum, moisture, pH levels, and sebum configuration on Demodex spp. density Materials and methods: Forty-five patients who had demodicosis were enrolled in the study group, while the control group consisted of 40 subjects without demodicosis. Body fat percentage, serum triglyceride and cholesterol levels, skin sebum, moisture, and pH levels were measured. Demodex spp. density was determined with a standardized skin surface biopsy. Sebum samples were taken from the forehead and a high-performance thin-layer chromatography (HPTLC) method was performed on these samples. Subsequently, densitometric analyses were applied to the HPTLC plates. Results: Demodex spp. were found on the cheeks and lived in an alkali environment. Skin sebum and moisture levels were low in all groups. The skin pH levels and cholesterol ester in the sebum configuration were determined to be significantly higher in the group with demodicosis. Conclusion: We suggest that Demodex spp. may use cholesterol ester in the sebum as nutriment. In other words, cholesterol ester may be a suitable growth medium for the proliferation of Demodex spp.en_US
dc.identifier.citationDemirdag, HG. Ozcan, H. Gursoy, S. Akbulut, GB. (2016). The effects of sebum configuration on Demodex spp. density. Cilt:46. Sayı:5. 1415- 1421 ss.en_US
dc.identifier.doi10.3906/sag-1504-77en_US
dc.identifier.endpage1421en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5en_US
dc.identifier.pmid27966307en_US
dc.identifier.scopus2-s2.0-84995807054en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1415en_US
dc.identifier.trdizinid251575en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1504-77
dc.identifier.urihttps://hdl.handle.net/11616/14479
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/251575
dc.identifier.volume46en_US
dc.identifier.wosWOS:000389053000022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubıtak scıentıfıc & technıcal research councıl turkey, ataturk bulvarı no 221, kavaklıdere, ankara, 00000, turkeyen_US
dc.relation.ispartofTurkısh journal of medıcal scıencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectKın-surface bıopsyen_US
dc.subjectfollıculorumen_US
dc.subjectdemodıcosısen_US
dc.subjectrosaceaen_US
dc.subjectlıpıdsen_US
dc.titleThe effects of sebum configuration on Demodex spp. densityen_US
dc.typeArticleen_US

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