Langerhans Cell Histiocytosis with Atypical Intervertebral Disc and Sacroiliac Joint Involvement Mimicking Osteoarticular Tuberculosis in an Adult

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dc.contributor.authorOzdemir, Zeynep Maras
dc.contributor.authorKahraman, Aysegul Sagir
dc.contributor.authorGormeli, Cemile Ayse
dc.contributor.authorSevimli, Resit
dc.contributor.authorAkpolat, Nusret
dc.date.accessioned2019-09-09T08:13:22Z
dc.date.available2019-09-09T08:13:22Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Langerhans cell histiocytosis (LCH), typically found in children, is a rare single or multisystem disorder with a wide range of clinical and radiological manifestations. Unusual presentations of LCH are occasionally encountered and it may be difficult to distinguish LCH from an infection or a benign or malignant tumor. Results: A 35-year-old female presented with pain in her back and left buttock, malaise, and weight loss, with a duration of several months. Her laboratory test results were within the normal ranges except for the levels of acute phase reactants, which were elevated. Magnetic resonance imaging and computed tomography revealed a unilateral destructive sacroiliac lesion, and multiple vertebral lesions with adjacent discal involvement and extensive soft tissue extensions. She was initially misdiagnosed with multifocal osteoarticular tuberculosis. An open biopsy and joint curettage was performed. Histopathological examination showed that she had LCH. Conclusion: To the best of our knowledge, this is the first case of LCH associated with a destructive unilateral sacroiliac lesion, discal involvement, and involvement of the adjacent vertebrae, in an adult patient; the LCH mimicked osteoarticular tuberculosis. Disease onset in adulthood is rare, and this can potentially delay diagnosis. Familiarity with the imaging features of unusual LCH manifestations is necessary to ensure accurate diagnosis and appropriate treatment.en_US
dc.identifier.citationOzdemir, ZM . Kahraman, AS . Gormeli, CA . Sevimli, R .Akpolat, N. (2016). Langerhans Cell Histiocytosis with Atypical Intervertebral Disc and Sacroiliac Joint Involvement Mimicking Osteoarticular Tuberculosis in an Adult. Cilt:33. Sayı:5. 573-577 ss.en_US
dc.identifier.doi10.5152/balkanmedj.2016.160492en_US
dc.identifier.endpage577en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue5en_US
dc.identifier.pmid27761291en_US
dc.identifier.scopus2-s2.0-84989327795en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage573en_US
dc.identifier.trdizinid204570en_US
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2016.160492
dc.identifier.urihttps://hdl.handle.net/11616/13906
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/204570
dc.identifier.volume33en_US
dc.identifier.wosWOS:000384744100018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAves, buyukdere cad 105-9, mecıdıyekoy, sıslı, ıstanbul 34394, turkeyen_US
dc.relation.ispartofBalkan medıcal journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectRadıotherapyen_US
dc.subjectextremıtıesen_US
dc.subjectboneen_US
dc.titleLangerhans Cell Histiocytosis with Atypical Intervertebral Disc and Sacroiliac Joint Involvement Mimicking Osteoarticular Tuberculosis in an Adulten_US
dc.typeArticleen_US

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