Synthesis of some heterocyclic phosphonates and their antibacterial and antifungal activities

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dc.authoridKUCUKBAY, HASAN/0000-0002-7180-9486
dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidKUCUKBAY, HASAN/A-5050-2019
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidDURMAZ, Rıza/HJH-4918-2023
dc.contributor.authorMete, A
dc.contributor.authorSener, S
dc.contributor.authorKücükbay, H
dc.contributor.authorGünal, S
dc.contributor.authorDurmaz, R
dc.date.accessioned2024-08-04T20:12:02Z
dc.date.available2024-08-04T20:12:02Z
dc.date.issued1999
dc.departmentİnönü Üniversitesien_US
dc.description.abstractFifteen heterocyclic phosphonate derivatives and their starting compounds have been evaluated in vitro for antibacterial and antifungal activities against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and yeast-like fungi; Candida albicans and Candida tropicalis. The compounds newly synthesised have been identified by H-1-NMR, FT-IR and micro analysis. Among the tested compounds 12, 13, 16, 17, 18, 22 and 23 are found effective to inhibit the growth of Candida albicans and Candida tropicalis at the MICs between 100-800 mu g/mL. The compounds tested here generally do not exhibit considerable antibacterial activity at the concentration studied (100-800 mu g/mL), except compound 18 which exhibits antibacterial activity against gram-positive bacteria at the MIC of 400 mu g/mL.en_US
dc.identifier.endpage200en_US
dc.identifier.issn0376-4699
dc.identifier.issn0019-5103
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0032998338en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://hdl.handle.net/11616/93174
dc.identifier.volume38en_US
dc.identifier.wosWOS:000079830300017en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCouncil Scientific & Industrial Resen_US
dc.relation.ispartofIndian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectDerivativesen_US
dc.subjectBenzimidazoleen_US
dc.titleSynthesis of some heterocyclic phosphonates and their antibacterial and antifungal activitiesen_US
dc.typeArticleen_US

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