The evaluation of the outcomes of long-term follow-up of patients with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome

Basit Öğe Kaydı
dc.authorscopusid23768445000
dc.authorscopusid10144697600
dc.authorscopusid6508003368
dc.authorscopusid24773824400
dc.authorscopusid55047448500
dc.authorscopusid26650216100
dc.contributor.authorTekin M.
dc.contributor.authorToplu Y.
dc.contributor.authorGülyüz A.
dc.contributor.authorKonca Ç.
dc.contributor.authorUzuner S.
dc.contributor.authorÜçkardeş F.
dc.date.accessioned2024-08-04T20:00:56Z
dc.date.available2024-08-04T20:00:56Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Evaluation of the long-term outcomes of patients as with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. Material and Methods: In this study, 57 patients admitted to the pediatrics and otorhinolaryngology clinics, and diagnosed as PFAPA syndrome, between 2005 and 2013 were analyzed retrospectively. Age, gender, age of attacks onset, age at diagnosis, frequency of attacks, duration of fever, the major clinical findings, concomitant clinical findings, seasonal difference in attack frequency, concomitant diseases during long term follow-up, the efficiency of single dose prednisolone (1 mg/kg) or tonsillectomy treatment and related resolution rates, and spontaneous remission rates were analyzed. Results: In this retrospective study, 57 patients diagnosed as PFAPA syndrome were followed for an median of 6.1 years (3-8 years). The number of patients whoes the attacks showed no seasonal differences were significantly higher than these showed seasonal differences (p<0.001). Asthma was the most common concomitant diseases with PFAPA syndrome. A single dose of prednisolone (1 mg/kg) was highly effective in controlling symptoms (in 96.4% of patients). Spontaneous remission of fever episodes was observed in twenty six patients during follow-up. The mean duration of disease was 6.6 years, and the mean age of remission was 8.9 years in patients with spontaneous remission. Tonsillectomy or adenotonsillectomy was performed to 10 patients and complete remission was observed in 8 of these patients. Totally 34 (60.7%) patients were recovered spontaneously or after tonsillectomy-adenotonsillectomy. Conclusion: In the long term follow-up, the most cases of patients diagnosed as PFAPA syndrome recovered spontaneously with no sequelae. Single dose of prednisolone (1 mg/kg) was highly effective in controlling symptoms. Tonsillectomy or adenotonsillectomy was very effective for permanent remission. Copyright © 2014 by Türkiye Klinikleri.en_US
dc.identifier.endpage15en_US
dc.identifier.issn1300-0381
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84901672501en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage10en_US
dc.identifier.urihttps://hdl.handle.net/11616/91126
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Pediatrien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComplicationsen_US
dc.subjectRemission, spontaneousen_US
dc.subjectTonsillectomyen_US
dc.titleThe evaluation of the outcomes of long-term follow-up of patients with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndromeen_US
dc.title.alternativePeriyodik ateş, aftöz stomatit, farenjit, servikal adenit (PFAPA) sendromlu hastalarin uzun dönem takip sonuçlarinin de?erlendirilmesien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu