Salusins, newly identified regulators of hemodynamics and mitogenesis, increase in polycystic ovarian syndrome

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dc.authoridCelik, ebru/0000-0002-0774-4294
dc.authoridMinareci, Yagmur/0000-0003-1420-9318
dc.authoridKaraer, Abdullah/0000-0002-2010-6211
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authorwosidCelik, ebru/X-4343-2019
dc.authorwosidMinareci, Yagmur/AAJ-7114-2021
dc.authorwosidSimsek, Yavuz/AAH-9894-2021
dc.authorwosidKaraer, Abdullah/ABI-4667-2020
dc.contributor.authorCelik, Onder
dc.contributor.authorYilmaz, Ercan
dc.contributor.authorCelik, Nilufer
dc.contributor.authorMinareci, Yagmur
dc.contributor.authorTurkcuoglu, Ilgin
dc.contributor.authorSimsek, Yavuz
dc.contributor.authorCelik, Ebru
dc.date.accessioned2024-08-04T20:36:14Z
dc.date.available2024-08-04T20:36:14Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn the current study, we aimed to investigate whether serum salusin alpha and beta levels are different in PCOS subjects. Fifty women with PCOS and 50 healthy, age-and body mass index matched controls were included to the prospective cross-sectional study. All subjects underwent venous blood drawing on the early follicular phase after an overnight fasting. Serum salusin alpha and beta levels were measured with EIA, and ELISA respectively. The relationships between serum salusin levels and anthropometric and metabolic parameters were also assessed. Plasma salusin alpha and beta levels were higher in women with PCOS compared to control group. Serum salusin alpha level correlated positively with salusin beta and fasting serum insulin levels. The serum salusin beta levels were correlated positively with HOMA-IR, TG, LDL-C, LH, FSH, and total testosterone levels. Our results indicate that salusins, newly identified regulators of hemodynamics and mitogenesis, are increased within the serum of women with PCOS.en_US
dc.identifier.doi10.3109/09513590.2012.706667
dc.identifier.endpage86en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue1en_US
dc.identifier.pmid22827297en_US
dc.identifier.scopus2-s2.0-84870567173en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.3109/09513590.2012.706667
dc.identifier.urihttps://hdl.handle.net/11616/95877
dc.identifier.volume29en_US
dc.identifier.wosWOS:000311683400018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiovascular risken_US
dc.subjectinsulin resistanceen_US
dc.subjectPCOSen_US
dc.subjectsalusin-alphaen_US
dc.subjectsalusin-betaen_US
dc.titleSalusins, newly identified regulators of hemodynamics and mitogenesis, increase in polycystic ovarian syndromeen_US
dc.typeArticleen_US

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