Effects of highly purified urinary FSH and human menopausal FSH on uterine myoelectrical dynamics

Küçük Resim Yok

Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Oxford Univ Press

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The aim of the study was to investigate the effects of urinary follicle-stimulating hormone (FSH) compounds on the electrical activity of myometrium using signal-processing techniques. Thirty animals were involved in the experiment. After two successive normal estrous cycles, 15 of these animals were put into three equal subgroups. Group 1 was the control; animals were given solvent. Groups 2 and 3 were treated with Urofollitropin and Menotropin, respectively. The other 15 animals were ovariectomized and subjected to the same protocol. Their uterine myoelectrical signals were recorded over a period of at least 3 min at a sampling frequency of 500 Hz, and analyzed through software assisted signal processing. The results show the power and some characteristic spectral components of myoelectrical signal were differentially reduced with the administration of highly purified urinary FSH and human menopausal FSH but significant differences were not detected between their histology. In conclusion, uterine myoelectrical signals change with administration of urinary FSH preparations. Human menopausal FSH and more precisely highly purified FSH suppress the spectral components and modify the power of the myoelectrical signals which provides uterine quiescence.

Açıklama

Anahtar Kelimeler

myoelectrical signal highly purified urinary FSH, human menopausal FSH, endometrium

Kaynak

Molecular Human Reproduction

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

16

Sayı

3

Künye